PRKAB2 and DAO

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		PRKAB2	DAO
Gene Name		protein kinase, AMP-activated, beta 2 non-catalytic subunit	D-amino-acid oxidase
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol AMP-activated Protein Kinase Complex	Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding Identical Protein Binding	D-amino-acid Oxidase Activity Receptor Binding Protein Binding Protein Dimerization Activity Cofactor Binding FAD Binding
	Biological Process	Energy Reserve Metabolic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Protein Kinase Activity Membrane Organization	Leucine Metabolic Process Proline Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process D-alanine Catabolic Process D-serine Metabolic Process
Pathways		Organelle biogenesis and maintenance Integration of energy metabolism Metabolism of lipids and lipoproteins Regulation of Rheb GTPase activity by AMPK IRS-mediated signalling mTOR signalling Translocation of GLUT4 to the plasma membrane Import of palmitoyl-CoA into the mitochondrial matrix mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade Signaling by Insulin receptor Fatty acid, triacylglycerol, and ketone body metabolism Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-related events Mitochondrial biogenesis IRS-mediated signalling Activation of PPARGC1A (PGC-1alpha) by phosphorylation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) AMPK inhibits chREBP transcriptional activation activity PKB-mediated events PI3K Cascade	Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs		Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions		70 interactors: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CCDC36 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FAM208B FDX1 FLNC GATA1 GATAD2B GET4 GNB2L1 GOLGA2 GRN IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PRDM14 PRKAA1 PRKAA2 PRKAG1 PRKAG2 PRKAG3 PSME3 PYGM RBPMS REL RHEBL1 RIMBP3 SPRY2 STX11 STX19 TADA2A TCF4 TP53BP2 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32	5 interactors: AOC1 DAOA EP300 PEX5 PRKAB2
Entrez ID		5565	1610
HPRD ID		04117	15917
Ensembl ID		ENSG00000131791	ENSG00000110887
Uniprot IDs		O43741	P14920
PDB IDs		2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2Y94 2YA3 4EAI 4EAJ	2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ
Enriched GO Terms of Interacting Partners?		Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Arrest Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Glycogen Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Cycle Energy Reserve Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Polysaccharide Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Organelle Organization Gene Expression Cell Cycle Process Positive Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Fatty Acid Biosynthetic Process Cellular Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Phosphorylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Death	Histone H2B Acetylation Cellular Response To Copper Ion Starvation Cellular Response To Azide Negative Regulation Of D-amino-acid Oxidase Activity Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation N-terminal Peptidyl-lysine Acetylation Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Heparin Regulation Of Tubulin Deacetylation Response To Heparin Cellular Response To Copper Ion Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Carnitine Shuttle Fatty Acid Metabolic Process Cellular Response To Histamine Negative Regulation Of Protein Oligomerization Positive Regulation By Host Of Viral Transcription Carnitine Transmembrane Transport Oxidation-reduction Process N-terminal Protein Amino Acid Acetylation Carnitine Transport Response To Histamine Mitochondrion Organization Protein Import Into Peroxisome Matrix Transmembrane Transport Cellular Response To Organonitrogen Compound Quaternary Ammonium Group Transport Cellular Response To Organic Substance Cellular Response To Ammonium Ion Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Oxidoreductase Activity Response To Copper Ion Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Monocarboxylic Acid Metabolic Process Very Long-chain Fatty Acid Metabolic Process N-terminal Protein Amino Acid Modification Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Regulation Of Fatty Acid Biosynthetic Process Monovalent Inorganic Cation Transport
Tagcloud ?			accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually
Tagcloud (Difference) ?			accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually
Tagcloud (Intersection) ?