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CSNK2B and SIMC1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CSNK2B
SIMC1
Gene Name
casein kinase 2, beta polypeptide
SUMO-interacting motifs containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Protein Kinase CK2 Complex
PcG Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Protein Serine/threonine Kinase Activity
Receptor Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Regulator Activity
Protein Domain Specific Binding
Identical Protein Binding
Metal Ion Binding
SUMO Polymer Binding
Biological Process
Mitotic Cell Cycle
Protein Phosphorylation
Signal Transduction
Axon Guidance
Negative Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Wnt Signaling Pathway
Positive Regulation Of Activin Receptor Signaling Pathway
Adiponectin-activated Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Cellular Protein Complex Assembly
Regulation Of Protein Kinase Activity
Regulation Of DNA Binding
Endothelial Tube Morphogenesis
Pathways
Mitotic Prometaphase
Signal transduction by L1
Axon guidance
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
L1CAM interactions
Signaling by Wnt
Cell Cycle, Mitotic
M Phase
WNT mediated activation of DVL
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by WNT in cancer
Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
175 interactors:
ABHD4
ACTB
ACTL6B
ACTR1B
ACTR5
ACVRL1
ADD1
ADH5
ADRBK1
ANGPT2
ANKRD28
AP2M1
APLP1
ARAF
ATF1
ATG101
ATXN3
BAG6
BCCIP
BID
BMI1
BRCA1
BTF3
C6orf136
C9orf114
CACNA1A
CALM1
CBX4
CCDC115
CCNH
CD163
CD81
CDC25B
CDC34
CDK1
CDK20
CDKN1A
CENPB
CHEK1
CHRNA4
CIC
COIL
COL4A2
COPS2
COPS3
COPS7A
CPNE7
CPSF3L
CSN1S1
CSN2
CSNK2A1
CSNK2A2
CTDP1
CTNNB1
DACT1
DALRD3
DENND5A
DNMT1
EIF2S2
EIF5
EIF6
EPS8
ERCC8
ESR1
FAF1
FBXL5
FGB
FGF1
FGF2
FIBP
FKBP3
FTH1
GADD45GIP1
GAMT
GBP2
GLB1
GNB5
HEXB
HIRIP3
HNRNPA2B1
HOXB6
HTRA1
IER3IP1
IRS1
ITSN1
JUN
KDM6B
KIF2C
LCK
LEPR
LMO4
LRP5L
LYN
LYST
MAPK14
MBD4
MGEA5
MME
MOXD1
MPP2
NAP1L1
NCF1
NMT2
NOLC1
NOTCH3
NRBP1
ODC1
PDS5A
PFKFB4
PHC2
PHF11
PHRF1
PIN1
PITPNA
PLXNA3
POT1
PPID
PPP3CC
PRKAB2
PRKCZ
PRNP
PROC
PTPRK
PYROXD2
RFC1
RNF126
RNF7
RPA1
RPL13
RPL41
RPL5
RPS6KA2
RPS6KA5
RPS6KB1
RPS6KB2
RRAD
RXRA
SARNP
SDHA
SEC11A
SHANK3
SHMT1
SHMT2
SIMC1
SIRT1
SNX2
SPSB3
SSB
STAT5A
STAU1
STK16
SUMO2
SYNE4
TCEAL7
TCTEX1D2
TLE1
TNFAIP1
TOP2B
TP53
TP53BP2
TSEN54
TUBB2B
UBE2I
UPF1
USO1
UTP14A
VDAC1
VRK3
WDR1
WDR18
WFIKKN1
ZNF44
ZNF71
ZNF784
ZNHIT1
6 interactors:
CSNK2B
DNAJB11
PLK1
TUBA4A
YWHAG
YWHAZ
Entrez ID
1460
375484
HPRD ID
00278
13486
Ensembl ID
ENSG00000204435
ENSG00000170085
Uniprot IDs
N0E4C7
P67870
Q5SRQ6
B4DRM7
Q8NDZ2
PDB IDs
1DS5
1JWH
1QF8
3EED
4DGL
Enriched GO Terms of Interacting Partners
?
Cellular Metabolic Process
Response To Growth Factor
Regulation Of Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Developmental Process
Cellular Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Cellular Protein Metabolic Process
Multicellular Organismal Development
Regulation Of Cell Proliferation
Anatomical Structure Development
Metabolic Process
Response To Organic Substance
Regulation Of Cellular Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell Cycle
Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
System Development
Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Response To Stimulus
Cell Cycle
Positive Regulation Of Protein Metabolic Process
Neurotrophin Signaling Pathway
Nitrogen Compound Metabolic Process
Biosynthetic Process
Cellular Protein Modification Process
Cellular Response To Stimulus
Cell Death
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Death
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Radiation
Response To Radiation
Positive Regulation Of Cell Proliferation
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Cellular Response To Light Stimulus
Gene Expression
Regulation Of Phosphorylation
Peptidyl-amino Acid Modification
Programmed Cell Death
Cellular Aromatic Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Protein Kinase Activity
Mitotic Cell Cycle
Regulation Of Kinase Activity
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Protein Phosphorylation
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Organelle Organization
Regulation Of Phosphorylation
Cell Cycle
Regulation Of Phosphorus Metabolic Process
Regulation Of Mitochondrion Organization
Mitotic Cell Cycle Process
Cellular Response To Stimulus
Negative Regulation Of Protein Serine/threonine Kinase Activity
Activation Of APC-Cdc20 Complex Activity
Cellular Response To Organic Substance
Positive Regulation Of Protein Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Membrane Organization
Positive Regulation Of Phosphorylation
Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Metabolic Process
Polar Body Extrusion After Meiotic Divisions
Golgi Reassembly
Platelet Activation
Positive Regulation Of Protein Modification Process
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Organelle Organization
Negative Regulation Of Protein Kinase Activity
Regulation Of Catalytic Activity
Cellular Localization
Negative Regulation Of Kinase Activity
Histamine Secretion By Mast Cell
Positive Regulation Of Intracellular Transport
Cell Cycle Process
Response To Organic Substance
Activation Of Anaphase-promoting Complex Activity
Meiotic Cytokinesis
Establishment Of Golgi Localization
Regulation Of Binding
Response To Stimulus
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Activin Receptor Signaling Pathway
Golgi Inheritance
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
bovine
casein
catalytic
cattle
chromosome
chromosomes
coast
composed
conserved
defined
east
encoding
fever
genomes
homology
hybrid
mapped
panel
parasitic
polymerase
rodent
segment
somatic
subunit
subunits
synteny
theileriosis
Tagcloud (Difference)
?
bovine
casein
catalytic
cattle
chromosome
chromosomes
coast
composed
conserved
defined
east
encoding
fever
genomes
homology
hybrid
mapped
panel
parasitic
polymerase
rodent
segment
somatic
subunit
subunits
synteny
theileriosis
Tagcloud (Intersection)
?