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PRKAB2 and CCDC33
Number of citations of the paper that reports this interaction (PMID
24722188
)
1
Data Source:
BioGRID
(two hybrid, two hybrid)
PRKAB2
CCDC33
Gene Name
protein kinase, AMP-activated, beta 2 non-catalytic subunit
coiled-coil domain containing 33
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytosol
AMP-activated Protein Kinase Complex
Molecular Function
AMP-activated Protein Kinase Activity
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Energy Reserve Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Fatty Acid Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Protein Kinase Activity
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Drugs
Adenosine monophosphate
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
70 interactors:
ADAMTSL4
BANP
BEND5
BLZF1
CALCOCO2
CASP6
CCDC33
CCDC36
CDX4
CREB3L1
CRX
CSNK2B
DAO
DDIT4L
DICER1
DST
EPM2A
FAM208B
FDX1
FLNC
GATA1
GATAD2B
GET4
GNB2L1
GOLGA2
GRN
IKZF1
IKZF3
KCTD5
KLF15
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LZTS2
MAGED1
MDFI
MEOX2
NEBL
PIAS2
PRDM14
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
PSME3
PYGM
RBPMS
REL
RHEBL1
RIMBP3
SPRY2
STX11
STX19
TADA2A
TCF4
TP53BP2
TRAF2
TRIM10
UBXN11
YY1AP1
ZBTB32
91 interactors:
ABCF3
ABLIM3
APP
ARIH2
ARMC7
ARNT2
BCCIP
BLK
BLZF1
BYSL
CALCOCO2
CCDC102B
CCDC85B
CCNH
CDCA7L
CDKN2B
CENPP
CHCHD3
DGCR6
DIP2A
DVL2
EFEMP2
EHMT2
EMC2
EMD
FAM124A
FAM161A
FXR2
GPATCH2L
GRN
HGS
HNRNPF
HNRNPK
HOOK2
HOXA1
ING5
KANK2
KCTD19
KCTD9
KHDRBS3
KIFC3
KXD1
LDOC1
LMO2
LMO3
MAGED1
MAPK9
MDFI
MIPOL1
MOS
NAB2
NCK2
NDOR1
NECAB2
NINL
OSGIN1
PID1
PIN1
PLSCR1
PNMA1
PNMA2
POLR1C
PPP2R3C
PRKAB2
PTGER3
PTK6
RAD54B
RBMX
RHOXF2
SCNM1
SMAD3
SPAG5
SPG21
SSSCA1
STK16
STX11
TGFB1
TMCC2
TRAF2
TRIM37
TRIM42
TSC22D4
TSGA10
TTC19
TUFT1
UBQLN4
USHBP1
VPS52
ZBTB8A
ZGPAT
ZNF572
Entrez ID
5565
80125
HPRD ID
04117
09959
Ensembl ID
ENSG00000131791
ENSG00000140481
Uniprot IDs
O43741
Q8N5R6
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2Y94
2YA3
4EAI
4EAJ
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Arrest
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Glycolytic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Polysaccharide Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Organelle Organization
Gene Expression
Cell Cycle Process
Positive Regulation Of Phosphorylation
RNA Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Fatty Acid Biosynthetic Process
Cellular Process
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Binding
Regulation Of Metabolic Process
Regulation Of Carbohydrate Metabolic Process
Regulation Of Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Death
Regulation Of Gene Expression
Regulation Of Protein Phosphorylation
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Protein Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Regulation Of Phosphorus Metabolic Process
RNA Metabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Proliferation
Negative Regulation Of Phosphorylation
Cellular Nitrogen Compound Metabolic Process
Immune System Process
Transcription From RNA Polymerase II Promoter
Cell Cycle Process
Evasion Or Tolerance Of Host Defenses By Virus
Regulation Of Cellular Process
Regulation Of Cell Cycle
Response To Organic Substance
Organelle Organization
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Proliferation
Positive Regulation Of MAP Kinase Activity
Nitrogen Compound Metabolic Process
Negative Regulation Of Protein Phosphorylation
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