PRKAB2 and BANP

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		PRKAB2	BANP
Gene Name		protein kinase, AMP-activated, beta 2 non-catalytic subunit	BTG3 associated nuclear protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol AMP-activated Protein Kinase Complex	Nucleoplasm
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding Identical Protein Binding	P53 Binding DNA Binding Protein Binding
	Biological Process	Energy Reserve Metabolic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Protein Kinase Activity Membrane Organization	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Multicellular Organismal Development Chromatin Modification Protein Localization To Nucleus Negative Regulation Of Protein Catabolic Process
Pathways		Organelle biogenesis and maintenance Integration of energy metabolism Metabolism of lipids and lipoproteins Regulation of Rheb GTPase activity by AMPK IRS-mediated signalling mTOR signalling Translocation of GLUT4 to the plasma membrane Import of palmitoyl-CoA into the mitochondrial matrix mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade Signaling by Insulin receptor Fatty acid, triacylglycerol, and ketone body metabolism Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-related events Mitochondrial biogenesis IRS-mediated signalling Activation of PPARGC1A (PGC-1alpha) by phosphorylation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) AMPK inhibits chREBP transcriptional activation activity PKB-mediated events PI3K Cascade
Drugs		Adenosine monophosphate
Diseases
GWAS			Central corneal thickness ( 20719862) Corneal structure ( 23291589)
Protein-Protein Interactions		70 interactors: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CCDC36 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FAM208B FDX1 FLNC GATA1 GATAD2B GET4 GNB2L1 GOLGA2 GRN IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PRDM14 PRKAA1 PRKAA2 PRKAG1 PRKAG2 PRKAG3 PSME3 PYGM RBPMS REL RHEBL1 RIMBP3 SPRY2 STX11 STX19 TADA2A TCF4 TP53BP2 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32	77 interactors: ADAM15 ALAS2 BAG5 BTG3 C1orf94 C22orf39 C6orf165 CAMK2D CCDC26 CEP76 COL10A1 DCDC2B DNAJA4 EPHA10 FAM117B FAM120C FAM71C FAM90A1 FHL2 FOXM1 FOXR1 GFM2 HMGB3P1 ISCU L3MBTL3 LACE1 LENG1 LGALS14 LINC00152 LINC01547 LMO2 LMO3 LMO4 LSM2 MAP2K1 MAX MIR4435-1HG MRPL28 MVP NEDD9 NRIP2 PHF21A PID1 PIM1 PML POGZ POLDIP3 POLR2L PPIB PPIC PPIF PRKAB2 PRKCH PRPF39 PSMD9 RAB3IP RBM39 RBPMS RIMS3 SH3RF2 SLC16A3 SNRPB SP2 SPACA6P TERF2 TERF2IP TNXB TOX4 TP53 TRAF2 TRAF4 TROAP ZC2HC1C ZMIZ2 ZNF471 ZNF488 ZNF581
Entrez ID		5565	54971
HPRD ID		04117	16538
Ensembl ID		ENSG00000131791	ENSG00000172530
Uniprot IDs		O43741	B3KM38 B4DE54 Q8N9N5 Q9NSS6
PDB IDs		2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2Y94 2YA3 4EAI 4EAJ
Enriched GO Terms of Interacting Partners?		Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Arrest Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Glycogen Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Cycle Energy Reserve Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Polysaccharide Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Organelle Organization Gene Expression Cell Cycle Process Positive Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Fatty Acid Biosynthetic Process Cellular Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Phosphorylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Death	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Metabolic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Cellular Senescence Negative Regulation Of Telomere Maintenance Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Process Regulation Of Telomere Maintenance Nitrogen Compound Metabolic Process Metabolic Process Regulation Of Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Cell Aging Protection From Non-homologous End Joining At Telomere Positive Regulation Of Cellular Metabolic Process Regulation Of Double-strand Break Repair Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Phosphorylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Signal Transduction Telomere Capping Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mitochondrion Organization Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Protein Localization To Chromosome, Telomeric Region Regulation Of Stress-activated MAPK Cascade Regulation Of Histone Deacetylation
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