Wiki-Pi
About
Search
People
Updates
Search
CSNK2B and LYN
Number of citations of the paper that reports this interaction (PubMedID
14667819
)
0
Data Source:
HPRD
(two hybrid)
CSNK2B
LYN
Description
casein kinase 2 beta
LYN proto-oncogene, Src family tyrosine kinase
Image
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Protein Kinase CK2 Complex
PML Body
PcG Protein Complex
Secretory Granule Lumen
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Nucleus
Cytoplasm
Lysosome
Lysosomal Membrane
Golgi Apparatus
Cytosol
Plasma Membrane
Adherens Junction
Cytoplasmic Side Of Plasma Membrane
Membrane
Mitochondrial Crista
Endocytic Vesicle Membrane
Mitochondrial Membrane
Protein-containing Complex
Integrin Alpha2-beta1 Complex
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Glutamatergic Synapse
Postsynaptic Specialization, Intracellular Component
Molecular Function
Chromatin Binding
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
Protein Kinase Regulator Activity
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Metal Ion Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Nucleotide Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Signaling Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
SH3 Domain Binding
Enzyme Binding
Signaling Receptor Activator Activity
Ubiquitin Protein Ligase Binding
Gamma-tubulin Binding
Glycosphingolipid Binding
Transmembrane Transporter Binding
Protein-containing Complex Binding
Ephrin Receptor Binding
Phosphoprotein Binding
Scaffold Protein Binding
Phosphorylation-dependent Protein Binding
Phosphatidylinositol 3-kinase Activator Activity
Biological Process
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Peptidyl-threonine Phosphorylation
Release From Viral Latency
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Activin Receptor Signaling Pathway
Adiponectin-activated Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of SMAD Protein Signal Transduction
Endothelial Tube Morphogenesis
Protein-containing Complex Assembly
Symbiont-mediated Disruption Of Host Cell PML Body
Negative Regulation Of Viral Life Cycle
DNA Damage Checkpoint Signaling
Cell Morphogenesis
B Cell Homeostasis
Regulation Of Cytokine Production
Regulation Of Protein Phosphorylation
Negative Regulation Of Protein Phosphorylation
Stimulatory C-type Lectin Receptor Signaling Pathway
Hematopoietic Progenitor Cell Differentiation
Adaptive Immune Response
Immune System Process
Fc Receptor Mediated Stimulatory Signaling Pathway
Tolerance Induction To Self Antigen
Histamine Secretion By Mast Cell
Platelet Degranulation
Innate Immune Response-activating Signaling Pathway
Negative Regulation Of Myeloid Leukocyte Differentiation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Fc Receptor Mediated Inhibitory Signaling Pathway
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of B Cell Apoptotic Process
Protein Phosphorylation
Autophagy
Response To Stress
Inflammatory Response
DNA Damage Response
Response To Sterol Depletion
Signal Transduction
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Response To Xenobiotic Stimulus
Response To Toxic Substance
Response To Hormone
Response To Carbohydrate
Positive Regulation Of Neuron Projection Development
Oligodendrocyte Development
Fatty Acid Transport
Peptidyl-tyrosine Phosphorylation
Hemopoiesis
Erythrocyte Differentiation
Eosinophil Differentiation
Positive Regulation Of Cell Migration
Negative Regulation Of B Cell Proliferation
Neuron Projection Development
T Cell Costimulation
Lipopolysaccharide-mediated Signaling Pathway
Response To Insulin
Regulation Of Mast Cell Activation
Regulation Of Cell Adhesion Mediated By Integrin
Negative Regulation Of Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Cellular Response To Heat
Intracellular Signal Transduction
Interleukin-5-mediated Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
C-X-C Chemokine Receptor CXCR4 Signaling Pathway
B Cell Proliferation
Positive Regulation Of Phosphorylation
Response To Amino Acid
Regulation Of Mast Cell Degranulation
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of MAPK Cascade
Response To Peptide Hormone
Innate Immune Response
Regulation Of Erythrocyte Differentiation
Protein Autophosphorylation
Ephrin Receptor Signaling Pathway
Response To Axon Injury
Regulation Of Inflammatory Response
Negative Regulation Of Immune Response
B Cell Receptor Signaling Pathway
Regulation Of B Cell Receptor Signaling Pathway
Negative Regulation Of B Cell Receptor Signaling Pathway
Leukocyte Migration
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Glial Cell Proliferation
Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Oligodendrocyte Progenitor Proliferation
Negative Regulation Of Mast Cell Proliferation
Positive Regulation Of Mast Cell Proliferation
Cellular Response To Retinoic Acid
Cellular Response To Lipid
Regulation Of Monocyte Chemotaxis
Regulation Of Platelet Aggregation
Dendritic Cell Differentiation
Neuroinflammatory Response
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Dendritic Cell Apoptotic Process
Pathways
Synthesis of PC
WNT mediated activation of DVL
Condensation of Prometaphase Chromosomes
Signal transduction by L1
Neutrophil degranulation
Regulation of TP53 Activity through Phosphorylation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Receptor Mediated Mitophagy
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN stability and activity
KEAP1-NFE2L2 pathway
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Maturation of hRSV A proteins
SPOP-mediated proteasomal degradation of PD-L1(CD274)
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
GPVI-mediated activation cascade
Signaling by SCF-KIT
Signaling by SCF-KIT
Regulation of KIT signaling
Cell surface interactions at the vascular wall
FCGR activation
PECAM1 interactions
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
EPH-Ephrin signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Co-stimulation by CD28
Co-inhibition by CTLA4
EPHB-mediated forward signaling
EPHB-mediated forward signaling
EPHA-mediated growth cone collapse
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells
Dectin-2 family
CD209 (DC-SIGN) signaling
CD22 mediated BCR regulation
Cyclin D associated events in G1
Platelet Adhesion to exposed collagen
Signaling by Erythropoietin
Signaling by Erythropoietin
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
Erythropoietin activates Phospholipase C gamma (PLCG)
Erythropoietin activates STAT5
Erythropoietin activates RAS
Erythropoietin activates RAS
Regulation of signaling by CBL
Regulation of signaling by CBL
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated phagocytosis
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
Signaling by CSF3 (G-CSF)
Signaling by CSF3 (G-CSF)
Signaling by CSF1 (M-CSF) in myeloid cells
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Growth hormone receptor signaling
Growth hormone receptor signaling
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
ATP
Quercetin
Dasatinib
1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
Bosutinib
Ponatinib
Nintedanib
Fostamatinib
Diseases
GWAS
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Cutaneous lupus erythematosus (
25827949
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Systemic lupus erythematosus (
26316170
)
Ulcerative colitis (
28067908
)
Granulocyte count (
27863252
)
Height (
18391951
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
27863252
32888494
)
Platelet count (
32888494
)
Refractive error (
32231278
)
Serum thyroid-stimulating hormone levels (
24852370
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
Systemic lupus erythematosus (
28714469
)
White blood cell count (
29403010
27863252
32888494
)
Interacting Genes
222 interacting genes:
ABHD4
ACTB
ACTL6B
ACTR1B
ACTR5
ACVRL1
ADD1
ADH5
ANGPT2
ANKRD28
AP2M1
APLP1
ARAF
ATF1
ATG101
ATXN3
BAG6
BANP
BCCIP
BHLHE41
BID
BMI1
BRCA1
BTF3
C6orf136
CACNA1A
CALM1
CCDC187
CCNB1
CCNH
CD163
CD81
CDC25B
CDC34
CDK1
CDK20
CDKN1A
CHEK1
CHRNA4
CIC
CIPC
CLOCK
COIL
COL4A2
COPS3
COPS7A
CPNE7
CREB1
CSN1S1
CSN2
CSNK1E
CSNK2A1
CSNK2A2
CST1
CTDP1
CTNNB1
DACT1
DALRD3
DAXX
DELEC1
DENND5A
DNMT1
DPF3
DSCAM
DUX1
DYNLT2B
EIF2S2
EIF5
EIF6
EPS8
ERCC6
ERCC8
ESR1
FAF1
FAM86C1P
FBXL15
FBXL5
FGB
FGF1
FGF2
FIBP
FKBP3
FTH1
FXR1
FXR2
GADD45GIP1
GAMT
GBP2
GLB1
GLIS2
GNB5
GRIN2A
GRIN2B
GRK2
GSK3B
HEXB
HNRNPA2B1
HOXB5
HOXB6
HTRA1
HYPK
IER3IP1
INO80B
INTS11
IRS1
ITSN1
KDM6B
KIF2C
LCK
LEPR
LMO4
LRP5L
LTB4R2
LYN
LYST
MAPK14
MBD4
MDM2
MME
MOXD1
MPP2
NAP1L1
NCF1
NGDN
NMT2
NOLC1
NOTCH3
NPAS2
NRBP1
NRF1
NTAQ1
ODC1
OGA
OGT
PDS5A
PER1
PER2
PFKFB4
PHF11
PIMREG
PIN1
PITPNA
PLXNA3
POT1
PPID
PPP1CA
PPP1CB
PPP1CC
PPP2CA
PPP2R1A
PPP2R1B
PPP2R5D
PPP2R5E
PPP3CC
PRKAB2
PRKCZ
PRNP
PROC
PTPRK
PTTG2
PYROXD2
RAD17
RAD51
RFC1
RNF126
RNF7
RORB
RPA1
RPL13
RPL41
RPL5
RPS6KB1
RRAD
RXRA
SARNP
SDHA
SEC11A
SELENOI
SHMT1
SHMT2
SIMC1
SNX2
SPOUT1
SPSB3
SSB
STAT5A
STAU1
STK16
SUMO2
SYNE4
TCEAL7
TENM1
TFAP2A
TFAP2D
TLE1
TLX3
TNFAIP1
TOP2B
TP53
TP53BP2
TP63
TRIM54
TSEN54
TUBB2B
TWF1
UBE2I
UPF1
USO1
UTP14A
VDAC1
VMA22
VRK3
WDR1
WDR18
WFIKKN1
WWOX
ZNF19
ZNF410
ZNF44
ZNF71
ZNF784
ZNHIT1
124 interacting genes:
ACTB
ADAM15
AR
BANK1
BCAR1
BTK
CASP3
CASP7
CASP9
CBL
CBLC
CD19
CD22
CD36
CD72
CD79A
CD79B
CDK1
CDK2
CDKN1B
CHST15
COASY
CREBBP
CRKL
CSF1R
CSF2RA
CSF2RB
CSF3R
CSK
CSNK2B
CTLA4
DAPP1
DLG4
DOK1
DOK2
DOK3
EGFR
EPOR
ERBB3
ERBB4
EVL
FASLG
FCAR
FCER1G
FCGR2A
FCGR2B
FOLR1
GAB2
GAB3
GP6
GRIA3
HCLS1
HNRNPK
IGHA1
IL1B
IL2RB
IL7R
INPP5D
ITPR1
JAK2
KHDRBS1
KIT
LCP2
LIME1
MAP4K1
MAPK3
MATK
MET
MME
MS4A1
MS4A2
MUC1
NDFIP2
NEDD9
NMT1
NPHS1
PAG1
PAK2
PDE4A
PDE4D
PECAM1
PIK3CG
PILRB
PLCG1
PLCG2
PPP1R15A
PPP1R8
PRAM1
PRKCD
PRKCQ
PRKDC
PRRG4
PTK2
PTK2B
PTPN6
PTPRC
RASA1
RGS16
RPL10
RPS6KB1
RPS6KB2
SH2B2
SHC1
SKAP1
SKAP2
SLC4A1
SNCA
SOCS1
SPHK1
SPHK2
STAT3
SYK
TEC
TNF
TRAT1
TRIM28
TRIM55
TRIM63
TRIP10
TRPV4
TYK2
UBB
UHRF2
UNC119
Entrez ID
1460
4067
HPRD ID
00278
01301
Ensembl ID
ENSG00000204435
ENSG00000254087
Uniprot IDs
A0A1U9X7J2
N0E4C7
P67870
A8K379
B4DQ79
P07948
Q6NUK7
PDB IDs
1DS5
1JWH
1QF8
3EED
4DGL
4MD7
4MD8
4MD9
4NH1
6Q38
1W1F
1WA7
3A4O
5XY1
6NMW
8WFF
Enriched GO Terms of Interacting Partners
?
Nucleus
Nucleoplasm
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Cytosol
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Protein Binding
Regulation Of Cell Cycle
Cytoplasm
Macromolecule Metabolic Process
Positive Regulation Of DNA Metabolic Process
DNA Damage Response
Rhythmic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of Circadian Rhythm
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Regulation Of Gene Expression
Chromosome Organization
Regulation Of Transcription By RNA Polymerase II
Response To Light Stimulus
Regulation Of Cell Cycle Process
Regulation Of RNA Metabolic Process
Regulation Of RNA Biosynthetic Process
Circadian Regulation Of Gene Expression
Nucleic Acid Metabolic Process
Circadian Rhythm
Positive Regulation Of RNA Biosynthetic Process
Regulation Of DNA-templated Transcription
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Programmed Cell Death
Photoperiodism
Negative Regulation Of Metabolic Process
DNA Damage Checkpoint Signaling
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of Macromolecule Metabolic Process
Cellular Response To Stress
Response To Radiation
Signal Transduction In Response To DNA Damage
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Biosynthetic Process
Cellular Response To Oxygen-containing Compound
Cell Cycle Phase Transition
Intracellular Signal Transduction
Cell Surface Receptor Signaling Pathway
Signal Transduction
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Immune System Process
Regulation Of Immune System Process
Immune Response-regulating Signaling Pathway
Immune System Process
Regulation Of Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Plasma Membrane
Antigen Receptor-mediated Signaling Pathway
Regulation Of Programmed Cell Death
Immune Response-activating Signaling Pathway
Positive Regulation Of Immune Response
Regulation Of Apoptotic Process
Intracellular Signal Transduction
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Activation Of Immune Response
Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
B Cell Receptor Signaling Pathway
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Enzyme-linked Receptor Protein Signaling Pathway
Adaptive Immune Response
Positive Regulation Of Cell Population Proliferation
Cytokine-mediated Signaling Pathway
Regulation Of Cell Population Proliferation
Regulation Of Cell Activation
Immune Response
T Cell Receptor Signaling Pathway
Protein Kinase Activity
Negative Regulation Of Programmed Cell Death
Kinase Activity
Phosphorylation
Protein Phosphorylation
Regulation Of Multicellular Organismal Process
B Cell Activation
Regulation Of Transport
Intracellular Signaling Cassette
Negative Regulation Of Apoptotic Process
Cell Activation
Regulation Of MAPK Cascade
External Side Of Plasma Membrane
Leukocyte Activation
Regulation Of Leukocyte Proliferation
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?