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PRKAB2 and KRT40
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PRKAB2
KRT40
Gene Name
protein kinase, AMP-activated, beta 2 non-catalytic subunit
keratin 40, type I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytosol
AMP-activated Protein Kinase Complex
Intermediate Filament
Molecular Function
AMP-activated Protein Kinase Activity
Protein Binding
Identical Protein Binding
Structural Molecule Activity
Biological Process
Energy Reserve Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Fatty Acid Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Protein Kinase Activity
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Drugs
Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions
70 interactors:
ADAMTSL4
BANP
BEND5
BLZF1
CALCOCO2
CASP6
CCDC33
CCDC36
CDX4
CREB3L1
CRX
CSNK2B
DAO
DDIT4L
DICER1
DST
EPM2A
FAM208B
FDX1
FLNC
GATA1
GATAD2B
GET4
GNB2L1
GOLGA2
GRN
IKZF1
IKZF3
KCTD5
KLF15
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LZTS2
MAGED1
MDFI
MEOX2
NEBL
PIAS2
PRDM14
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
PSME3
PYGM
RBPMS
REL
RHEBL1
RIMBP3
SPRY2
STX11
STX19
TADA2A
TCF4
TP53BP2
TRAF2
TRIM10
UBXN11
YY1AP1
ZBTB32
313 interactors:
ADAMTSL3
AEN
AES
AKAP17A
ALDH3B1
ALS2CR11
ANKRD36BP1
AP1M1
AQP1
AQP5
ARID5A
ARMC7
ARSI
ASMTL
ATPAF2
AVPI1
BAHD1
BARD1
BCAS2
BEX2
BMS1P5
BYSL
C10orf62
C11orf87
C14orf105
C19orf57
C19orf66
C19orf73
C1orf109
C1orf216
C20orf195
C22orf46
C5orf60
C6orf165
C6orf226
C8orf48
CA6
CARD9
CATIP
CBX8
CCDC112
CCDC120
CCDC146
CCDC185
CCDC26
CCDC93
CCER1
CCHCR1
CCNG1
CD33
CDC20B
CDK18
CDK5R1
CELA2B
CEP57
CEP57L1
CHCHD2
CHCHD3
CHIC2
CLEC18A
CNTF
COL8A1
COMT
COX5A
CREB5
CTSZ
CWF19L2
CYCS
CYTH4
DAAM2
DCDC2B
DCX
DDX6
DLGAP2
DMRT3
DOCK2
DOCK8
DTNB
EIF4E2
EXOC3-AS1
FAM107A
FAM124B
FAM214A
FAM27E3
FAM64A
FAM71C
FAM74A4
FAM90A1
FARS2
FASLG
FBF1
FBXL18
FBXO34
FBXW5
FKBP1B
FOXB1
FRG1
GATA2
GATAD2A
GEM
GFOD1
GGN
GLIDR
GNAI2
GNG5
GOLGA6L2
GPATCH2L
GTF3C5
GUCD1
HAUS1
HBA2
HBZ
HCK
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ING5
INPP5D
IQUB
ISCU
ITGB5
JOSD1
KAT5
KCTD9
KIFC3
KLHL38
KPNA2
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT8
KRT81
LAGE3
LCE3E
LENG1
LIMS2
LIN37
LINC00636
LINC01588
LMF2
LMO1
LMO2
LMO4
LOC149950
LRCH4
MAB21L2
MAGOHB
MAPKBP1
MARK4
MED8
METTL17
MFAP1
MOB3C
MOS
MRPL11
MTA1
MXI1
NAB2
NAPRT
NDEL1
NEK6
NFKBID
NINJ1
NPBWR2
NPPB
NR1D2
NXF1
OPCML
OTUB2
PDLIM5
PGLS
PHF21A
PIGS
PIN1
PKD2
POLDIP3
POLL
POM121L8P
POP5
PPP1R18
PRAM1
PRKAA1
PRKAB2
PRPF31
PSMA1
PSMC5
PTGER3
PTPMT1
PXMP2
QPRT
RAB3IL1
RAB3IP
RAC1
RASSF5
RBM41
RCOR3
RECK
RNF213
RPL11
RSPH14
RTP5
RWDD2B
SCOC
SEMA4C
SETD5
SH2D4A
SHC3
SIRPA
SLC25A10
SLIRP
SLU7
SMARCE1
SMCO4
SNAI1
SNHG11
SNRPB
SNW1
SPATA24
SPEF1
SPG7
SRSF2
SSX2
SSX2IP
SYT6
TAPBPL
TBC1D16
TBC1D22B
TCEA2
TCEB3
TCHP
THAP7
TIE1
TMEM231
TMEM241
TMSB4X
TNIP3
TNNT1
TRAF4
TRIM42
TROAP
TRPV6
TSC22D4
TSGA10IP
TSHZ3
TTC23
TTC25
TTLL10
TXLNA
TXN2
TXNDC5
TYK2
TYRO3
UACA
UBASH3A
UCMA
USHBP1
USP2
USP21
UTP14C
UTP23
UXT
WDR25
WT1
WT1-AS
ZBTB16
ZBTB24
ZBTB38
ZC2HC1C
ZFHX3
ZFP2
ZFP69B
ZFYVE21
ZFYVE26
ZGPAT
ZMAT2
ZNF101
ZNF124
ZNF138
ZNF165
ZNF20
ZNF202
ZNF230
ZNF250
ZNF26
ZNF266
ZNF286A
ZNF317
ZNF329
ZNF337
ZNF417
ZNF439
ZNF446
ZNF488
ZNF490
ZNF564
ZNF569
ZNF581
ZNF587
ZNF625
ZNF655
ZNF697
ZNF702P
ZNF792
ZNF844
ZNRF2P1
ZSCAN21
Entrez ID
5565
125115
HPRD ID
04117
08304
Ensembl ID
ENSG00000131791
ENSG00000204889
Uniprot IDs
O43741
Q6A162
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2Y94
2YA3
4EAI
4EAJ
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Arrest
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Glycolytic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Polysaccharide Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Organelle Organization
Gene Expression
Cell Cycle Process
Positive Regulation Of Phosphorylation
RNA Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Fatty Acid Biosynthetic Process
Cellular Process
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Binding
Regulation Of Metabolic Process
Regulation Of Carbohydrate Metabolic Process
Regulation Of Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Death
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Cellular Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Defense Response To Virus By Virus
Regulation Of Cell Death
Regulation Of Protein Metabolic Process
Anatomical Structure Development
Regulation Of Apoptotic Process
Bicarbonate Transport
Cell Death
Death
Centrosome Organization
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Intermediate Filament Cytoskeleton Organization
Cytoskeleton Organization
Microtubule Organizing Center Organization
Positive Regulation Of Cellular Protein Metabolic Process
Intermediate Filament-based Process
Organelle Organization
Multicellular Organismal Development
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Tagcloud (Difference)
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Tagcloud (Intersection)
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