PRKAB2 and KRTAP9-2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRKAB2	KRTAP9-2
Gene Name		protein kinase, AMP-activated, beta 2 non-catalytic subunit	keratin associated protein 9-2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol AMP-activated Protein Kinase Complex	Keratin Filament
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding Identical Protein Binding
	Biological Process	Energy Reserve Metabolic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Protein Kinase Activity Membrane Organization
Pathways		Organelle biogenesis and maintenance Integration of energy metabolism Metabolism of lipids and lipoproteins Regulation of Rheb GTPase activity by AMPK IRS-mediated signalling mTOR signalling Translocation of GLUT4 to the plasma membrane Import of palmitoyl-CoA into the mitochondrial matrix mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade Signaling by Insulin receptor Fatty acid, triacylglycerol, and ketone body metabolism Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-related events Mitochondrial biogenesis IRS-mediated signalling Activation of PPARGC1A (PGC-1alpha) by phosphorylation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) AMPK inhibits chREBP transcriptional activation activity PKB-mediated events PI3K Cascade
Drugs		Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions		70 interactors: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CCDC36 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FAM208B FDX1 FLNC GATA1 GATAD2B GET4 GNB2L1 GOLGA2 GRN IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PRDM14 PRKAA1 PRKAA2 PRKAG1 PRKAG2 PRKAG3 PSME3 PYGM RBPMS REL RHEBL1 RIMBP3 SPRY2 STX11 STX19 TADA2A TCF4 TP53BP2 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32	54 interactors: ADAMTSL4 AQP1 ARFGAP1 C19orf66 CATSPER1 CCDC28A CHRD COL8A1 CREB5 DOCK2 FAM76B GATA1 GLRX3 GNE HOXA1 JOSD1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-4 LCE1B LCE2A LCE3E LCE4A LNX1 MAPKBP1 MEOX2 NOTCH2NL NUFIP2 OTX1 PDE9A PLSCR1 PRKAB2 PTPMT1 RCHY1 RNF31 SMCP SPATA8 SPRY2 SUMO1P1 TMSB10 WDYHV1 ZDHHC17
Entrez ID		5565	83899
HPRD ID		04117	13949
Ensembl ID		ENSG00000131791	ENSG00000239886
Uniprot IDs		O43741	Q9BYQ4
PDB IDs		2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2Y94 2YA3 4EAI 4EAJ
Enriched GO Terms of Interacting Partners?		Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Arrest Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Glycogen Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Cycle Energy Reserve Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Polysaccharide Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Organelle Organization Gene Expression Cell Cycle Process Positive Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Fatty Acid Biosynthetic Process Cellular Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Phosphorylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Death	Keratinization Keratinocyte Differentiation Epithelium Development Tissue Development Organ Development Epidermis Development Epidermal Cell Differentiation Developmental Process Skin Development Multicellular Organismal Development Inner Ear Morphogenesis Cell Differentiation Ear Morphogenesis Embryo Development System Development Sensory Organ Development BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Localization Within Membrane Ammonium Transmembrane Transport Anatomical Structure Development Embryonic Morphogenesis Establishment Or Maintenance Of Cell Polarity Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Myeloid Dendritic Cell Activation Involved In Immune Response Facial Nucleus Development Basophil Differentiation Carbon Dioxide Transmembrane Transport Corticotropin Secretion CD40 Signaling Pathway Eosinophil Fate Commitment N-acetylglucosamine Biosynthetic Process Establishment Or Maintenance Of Actin Cytoskeleton Polarity Sperm Motility Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell-cell Recognition Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Eosinophil Differentiation Metanephric Proximal Convoluted Tubule Development Rhombomere 4 Development Nitric Oxide Transport Semicircular Canal Formation Transcriptional Activation By Promoter-enhancer Looping
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