KIF9 and STEEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIF9	STEEP1
Description		kinesin family member 9	STING1 ER exit protein 1
Image
GO Annotations	Cellular Component	Podosome Cytoplasm Cytoskeleton Kinesin Complex Microtubule Cilium Motile Cilium Vesicle Sperm Flagellum Cell Projection	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Membrane Cell Body
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Identical Protein Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Microtubule-based Movement Extracellular Matrix Disassembly Regulation Of Podosome Assembly Regulation Of Flagellated Sperm Motility Organelle Disassembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Type I Interferon Production Protein Exit From Endoplasmic Reticulum Endoplasmic Reticulum Membrane Organization CGAS/STING Signaling Pathway
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Huntington's disease progression ( 28642124) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		63 interacting genes: ACBD4 ALAS1 AMOTL2 ATP5IF1 BLZF1 CARD9 CCDC125 CYTIP DISC1 EFHC2 EMD FXR1 GOLGA6A HMBOX1 HOOK2 HSF2BP IHO1 IKZF1 IKZF3 INKA1 IQCB1 JAKMIP2 KANK2 KCTD9 KRT75 KRTAP10-3 KRTAP10-6 KRTAP10-9 LZTS1 LZTS2 MAD1L1 MID1 MID2 MIPOL1 NAB2 OIP5 OOEP PIBF1 PNMA5 PPP1R13B PRICKLE1 PRMT6 RBM48 RBM5 ROPN1 SHISA6 SLAIN1 SSX2IP STEEP1 TFIP11 TRIM27 TRIM37 TRIM54 VIM VPS52 ZBTB8A ZC2HC1C ZCCHC7 ZNF417 ZNF436 ZNF566 ZNF572 ZRANB1	9 interacting genes: APP CEBPA HAT1 KIF9 PDCL2 PIBF1 RBM4 RPRD1B SNW1
Entrez ID		64147	63932
HPRD ID		07444	06541
Ensembl ID		ENSG00000088727	ENSG00000018610
Uniprot IDs		A8K932 Q6PJI1 Q9HAQ2	Q9H5V9
PDB IDs		3NWN	8C6J 9FMD
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Organelle Organization Microtubule Protein Localization To Cytoskeleton Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Intermediate Filament Negative Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament Zinc Ion Binding Wnt Signaling Pathway	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Negative Regulation Of Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Positive Regulation Of Gene Expression Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Endothelin Production Negative Regulation Of Macromolecule Biosynthetic Process Growth Cone Filopodium Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Lipoprotein Particle Positive Regulation Of Cell Differentiation Microtubule-based Process Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Microtubule-based Movement Positive Regulation Of Macromolecule Biosynthetic Process CHOP-C/EBP Complex Nuclear Matrix RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Cap-independent Translational Initiation Pre-mRNA Intronic Pyrimidine-rich Binding MRNA Processing IRES-dependent Translational Initiation Of Linear MRNA Circadian Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Interleukin-4 Receptor Binding Negative Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Cellular Response To Norepinephrine Stimulus Memory Astrocyte Activation Involved In Immune Response
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