KIF9 and ATP5IF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIF9	ATP5IF1
Description		kinesin family member 9	ATP synthase inhibitory factor subunit 1
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GO Annotations	Cellular Component	Podosome Cytoplasm Cytoskeleton Kinesin Complex Microtubule Cilium Motile Cilium Vesicle Sperm Flagellum Cell Projection	Cytoplasm Mitochondrion Cell Surface Protein-containing Complex
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Identical Protein Binding	Enzyme Inhibitor Activity Protein Binding Calmodulin Binding Enzyme Binding ATPase Inhibitor Activity Identical Protein Binding Angiostatin Binding ATPase Binding Mitochondrial Proton-transporting ATP Synthase Complex Binding
	Biological Process	Microtubule-based Movement Extracellular Matrix Disassembly Regulation Of Podosome Assembly Regulation Of Flagellated Sperm Motility Organelle Disassembly	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Generation Of Precursor Metabolites And Energy Heme Biosynthetic Process Erythrocyte Differentiation Negative Regulation Of Hydrolase Activity Mitochondrial Depolarization Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Targeting To Mitochondrion Regulation Of ATP Metabolic Process Positive Regulation Of Type 2 Mitophagy Negative Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Huntington's disease progression ( 28642124) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		63 interacting genes: ACBD4 ALAS1 AMOTL2 ATP5IF1 BLZF1 CARD9 CCDC125 CYTIP DISC1 EFHC2 EMD FXR1 GOLGA6A HMBOX1 HOOK2 HSF2BP IHO1 IKZF1 IKZF3 INKA1 IQCB1 JAKMIP2 KANK2 KCTD9 KRT75 KRTAP10-3 KRTAP10-6 KRTAP10-9 LZTS1 LZTS2 MAD1L1 MID1 MID2 MIPOL1 NAB2 OIP5 OOEP PIBF1 PNMA5 PPP1R13B PRICKLE1 PRMT6 RBM48 RBM5 ROPN1 SHISA6 SLAIN1 SSX2IP STEEP1 TFIP11 TRIM27 TRIM37 TRIM54 VIM VPS52 ZBTB8A ZC2HC1C ZCCHC7 ZNF417 ZNF436 ZNF566 ZNF572 ZRANB1	7 interacting genes: CDC42 CHD3 GSK3B KIF9 PICK1 PIK3CA UBQLN4
Entrez ID		64147	93974
HPRD ID		07444	16529
Ensembl ID		ENSG00000088727	ENSG00000130770
Uniprot IDs		A8K932 Q6PJI1 Q9HAQ2	Q9UII2
PDB IDs		3NWN	8H9E 8H9L 8H9S 8H9U 8KI3
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Organelle Organization Microtubule Protein Localization To Cytoskeleton Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Intermediate Filament Negative Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament Zinc Ion Binding Wnt Signaling Pathway	Neuron Projection Organization Regulation Of Organelle Organization Negative Regulation Of Cellular Component Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Cytoskeleton Organization Regulation Of Cell Projection Assembly Positive Regulation Of Lamellipodium Organization Regulation Of Cellular Component Organization Positive Regulation Of Lamellipodium Assembly Dendritic Spine Organization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Lamellipodium Assembly Negative Regulation Of Macroautophagy Regulation Of Actin Filament Organization Postsynapse Organization Nucleotide Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Lamellipodium Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Projection Organization Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Negative Regulation Of Catabolic Process Regulation Of Autophagy Regulation Of Microtubule Anchoring At Centrosome Insulin Receptor Signaling Pathway Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Stem Cell Differentiation Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cellular Component Organization Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Establishment Of Cell Polarity GBD Domain Binding Storage Vacuole Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Autophagy Nuclear Proteasome Complex Positive Regulation Of Cellular Component Biogenesis Organelle Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Cell-substrate Adhesion ATP Binding Regulation Of Generation Of Precursor Metabolites And Energy Response To Butyrate Cellular Response To Hydrostatic Pressure Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Autophagosome Maturation
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