PMP22 and PEX19

Number of citations of the paper that reports this interaction (PMID 10704444)
47

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		PMP22	PEX19
Gene Name		peripheral myelin protein 22	peroxisomal biogenesis factor 19
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Tight Junction Integral Component Of Membrane Compact Myelin	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Binding	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways			ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS		Corneal structure ( 23291589)
Protein-Protein Interactions		6 interactors: CANX DDX52 KLRC1 MPZ PEX19 SMIM3	32 interactors: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		5376	5824
HPRD ID		03059	02610
Ensembl ID		ENSG00000109099	ENSG00000162735
Uniprot IDs		Q01453 Q6FH25	P40855
PDB IDs			2W85 2WL8 3AJB 3MK4
Enriched GO Terms of Interacting Partners?		Chaperone-mediated Protein Folding Negative Regulation Of Lipid Binding Peroxisome Membrane Biogenesis Protein Folding Chaperone-mediated Protein Transport Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Cell-cell Junction Maintenance Peroxisome Fission Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Cellular Component Maintenance Membrane Biogenesis Synaptic Transmission Synaptic Vesicle Endocytosis Clathrin-mediated Endocytosis Synaptic Vesicle Recycling	Peroxisome Organization Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Peroxisomal Membrane Transport Protein Import Peroxisome Membrane Biogenesis Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Protein Import Into Peroxisome Membrane Organelle Organization Protein To Membrane Docking Transmembrane Transport Establishment Of Protein Localization To Organelle Fatty Acid Beta-oxidation Protein Targeting Cellular Lipid Catabolic Process Protein Localization To Organelle Regulation Of Peroxisome Size Lipid Modification Membrane Biogenesis Carboxylic Acid Catabolic Process Protein Import Into Peroxisome Matrix, Docking Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Cytoplasmic Transport Fatty Acid Alpha-oxidation Fatty Acid Metabolic Process Establishment Of Protein Localization Peroxisome Fission Intracellular Transport Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Establishment Of Protein Localization To Membrane Cellular Protein Localization Protein Stabilization Membrane Docking Posttranscriptional Regulation Of Gene Expression Protein Transport Positive Regulation Of Viral Genome Replication Cellular Component Assembly Regulation Of Defense Response To Virus By Host Monocarboxylic Acid Metabolic Process
Tagcloud ?		17q acrocentric anchor backcross centromeric cfa9 cryba1 distally dog galk1 gh1 giemsa hsa17 hsa17p hsa17q interbreed lie loosely mmu11 myl4 nf1 p4hb paint painting spanning syntenic thirds thra1 tk1	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Difference) ?		17q acrocentric anchor backcross centromeric cfa9 cryba1 distally dog galk1 gh1 giemsa hsa17 hsa17p hsa17q interbreed lie loosely mmu11 myl4 nf1 p4hb paint painting spanning syntenic thirds thra1 tk1	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Intersection) ?