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UBASH3A and TRIM37
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
UBASH3A
TRIM37
Gene Name
ubiquitin associated and SH3 domain containing A
tripartite motif containing 37
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Extracellular Vesicular Exosome
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Regulation Of Cytokine Production
Negative Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Celiac disease and Rheumatoid arthritis (
21383967
)
Rheumatoid arthritis (
20453842
)
Type 1 diabetes (
19430480
18840781
)
Type 1 diabetes autoantibodies (
21829393
)
Vitiligo (
20410501
)
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
14 interactors:
CBL
CBS
DAZAP2
KCNE1
KRT40
PARK2
REL
SF3B4
SPRY2
TP53BP2
TRIM37
UBB
UBC
UBE2L3
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
Entrez ID
53347
4591
HPRD ID
06904
05463
Ensembl ID
ENSG00000160185
ENSG00000108395
Uniprot IDs
P57075
A8K0V9
A8K8U4
F8WEE6
O94972
PDB IDs
2CRN
3LRQ
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Protein Polyubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Protein Ubiquitination
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cell Death
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Organic Substance
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Cellular Response To Organic Substance
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Transferase Activity
Viral Protein Processing
Positive Regulation Of Protein Metabolic Process
Aggresome Assembly
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Signal Transduction By P53 Class Mediator
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Positive Regulation Of Protein Modification Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cell Cycle
Notch Receptor Processing
Virion Assembly
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Glycogen Biosynthetic Process
Intracellular Transport Of Virus
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
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