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UBASH3A and TP53BP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
UBASH3A
TP53BP2
Gene Name
ubiquitin associated and SH3 domain containing A
tumor protein p53 binding protein 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Perinuclear Region Of Cytoplasm
Molecular Function
SH3/SH2 Adaptor Activity
Protein Binding
SH3 Domain Binding
Identical Protein Binding
NF-kappaB Binding
Biological Process
Regulation Of Cytokine Production
Negative Regulation Of T Cell Receptor Signaling Pathway
Cell Cycle
Signal Transduction
Central Nervous System Development
Heart Development
Embryo Development Ending In Birth Or Egg Hatching
Positive Regulation Of Signal Transduction
Response To Ionizing Radiation
Negative Regulation Of Cell Cycle
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS
Celiac disease and Rheumatoid arthritis (
21383967
)
Rheumatoid arthritis (
20453842
)
Type 1 diabetes (
19430480
18840781
)
Type 1 diabetes autoantibodies (
21829393
)
Vitiligo (
20410501
)
Protein-Protein Interactions
14 interactors:
CBL
CBS
DAZAP2
KCNE1
KRT40
PARK2
REL
SF3B4
SPRY2
TP53BP2
TRIM37
UBB
UBC
UBE2L3
58 interactors:
APP
ATPAF2
ATXN7
BAIAP2
BCL2
BCL2L1
CCDC92
CSNK2B
CWF19L2
DCUN1D1
EEF1A1
GRB2
HIST1H2BC
HNRNPUL1
KIF5A
LMO4
MAGI1
MAPK8IP2
MRPL20
MTMR14
NAE1
NDC80
NUTM1
OTUB2
PLEKHN1
PLK1
POLR2L
PPHLN1
PPP1CA
PPP1CB
PPP1CC
PRKAB2
PRPF31
PTN
RELA
SIAH1
SIAH2
SSX2IP
SUMO2
SUMO3
TANK
TBC1D22B
TCL1A
TP53
TRAF4
TXLNA
UBASH3A
UNC119
USP4
UTP14A
WWP1
WWP2
YAP1
YES1
YWHAG
YWHAQ
ZGPAT
ZNF26
Entrez ID
53347
7159
HPRD ID
06904
11803
Ensembl ID
ENSG00000160185
ENSG00000143514
Uniprot IDs
P57075
Q13625
PDB IDs
2CRN
1YCS
2UWQ
4A63
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Protein Polyubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Protein Ubiquitination
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cell Death
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Organic Substance
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Cellular Response To Organic Substance
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Transferase Activity
Viral Protein Processing
Positive Regulation Of Protein Metabolic Process
Aggresome Assembly
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Signal Transduction By P53 Class Mediator
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Positive Regulation Of Protein Modification Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cell Cycle
Notch Receptor Processing
Virion Assembly
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Glycogen Biosynthetic Process
Intracellular Transport Of Virus
Neuron Death
Neuron Apoptotic Process
Response To Radiation
Regulation Of Signal Transduction
Regulation Of Signaling
Response To External Stimulus
Negative Regulation Of Signal Transduction
Entrainment Of Circadian Clock By Photoperiod
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Negative Regulation Of Signaling
Photoperiodism
Entrainment Of Circadian Clock
Positive Regulation Of Apoptotic Signaling Pathway
Cell Part Morphogenesis
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Phosphorylation
Response To Light Stimulus
Protein Modification By Small Protein Conjugation
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cell Cycle
Neuron Projection Morphogenesis
Regulation Of Mitochondrion Organization
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cell Projection Morphogenesis
Axonogenesis
Cellular Protein Modification Process
Positive Regulation Of Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Cell Morphogenesis
Regulation Of Protein Metabolic Process
Cell Morphogenesis Involved In Differentiation
Regulation Of Cellular Protein Metabolic Process
Response To Gamma Radiation
Axon Development
Regulation Of Extrinsic Apoptotic Signaling Pathway
Mitotic Cell Cycle
Generation Of Neurons
Nervous System Development
Cellular Response To Ionizing Radiation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Innate Immune Response
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Neuron Projection Development
Neurogenesis
Anatomical Structure Morphogenesis
Tagcloud
?
adenovirus
angiotensin
apoptosis
array
at2r
bag3
bmp6
bmp7
bnipi
cytokine
downregulation
du145
gadd45a
hrk
il6
il8
mapk
microrna
next
numerous
p44
pc
r2
silence
sirnas
tnfsf10
trail
transduced
utilized
Tagcloud (Difference)
?
adenovirus
angiotensin
apoptosis
array
at2r
bag3
bmp6
bmp7
bnipi
cytokine
downregulation
du145
gadd45a
hrk
il6
il8
mapk
microrna
next
numerous
p44
pc
r2
silence
sirnas
tnfsf10
trail
transduced
utilized
Tagcloud (Intersection)
?