APH1A and PSEN2

  • Number of citations of the paper that reports this interaction (PMID 12297508)
  • 39
  • Data Source:
  • HPRD (in vitro, in vivo)

APH1A

PSEN2

Gene Name APH1A gamma secretase subunit presenilin 2
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 15 interactors: ATF4 BHLHE40 GLP1R GPATCH8 HES1 HIVEP1 KLF11 NCSTN PSEN1 PSEN2 PSENEN RBFOX2 THPO TLE1 TMED10 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 51107 5664
HPRD ID 06360 02860
Ensembl ID ENSG00000117362 ENSG00000143801
Uniprot IDs B4DUG7 Q96BI3 P49810
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aph1b  belonging  categorize  clarify  cleave  consequently  exclusive  fall  gamma  heterogeneous  histopathological  implying  intensively  kaplan  meier  mutually  nicastrin  pen  presenilin  probability  probable  proteolytically  secretase  transmembrane  treatable  triple  ubiquitously  univariate 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
aph1b  belonging  categorize  clarify  cleave  consequently  exclusive  fall  gamma  heterogeneous  histopathological  implying  intensively  kaplan  meier  mutually  nicastrin  pen  presenilin  probability  probable  proteolytically  secretase  transmembrane  treatable  triple  ubiquitously  univariate 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?