APH1A and PSEN1

  • Number of citations of the paper that reports this interaction (PMID 12297508)
  • 39
  • Data Source:
  • HPRD (in vitro, in vivo)

APH1A

PSEN1

Gene Name APH1A gamma secretase subunit presenilin 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 15 interactors: ATF4 BHLHE40 GLP1R GPATCH8 HES1 HIVEP1 KLF11 NCSTN PSEN1 PSEN2 PSENEN RBFOX2 THPO TLE1 TMED10 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1
Entrez ID 51107 5663
HPRD ID 06360 00087
Ensembl ID ENSG00000117362 ENSG00000080815
Uniprot IDs B4DUG7 Q96BI3 P49768
PDB IDs 2KR6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aph1b  belonging  categorize  clarify  cleave  consequently  exclusive  fall  gamma  heterogeneous  histopathological  implying  intensively  kaplan  meier  mutually  nicastrin  pen  presenilin  probability  probable  proteolytically  secretase  transmembrane  treatable  triple  ubiquitously  univariate 
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
Tagcloud (Difference) ?
aph1b  belonging  categorize  clarify  cleave  consequently  exclusive  fall  gamma  heterogeneous  histopathological  implying  intensively  kaplan  meier  mutually  nicastrin  pen  presenilin  probability  probable  proteolytically  secretase  transmembrane  treatable  triple  ubiquitously  univariate 
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
Tagcloud (Intersection) ?