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PCBD1 and SUPT5H
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
PCBD1
SUPT5H
Gene Name
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
suppressor of Ty 5 homolog (S. cerevisiae)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
DSIF Complex
Molecular Function
Transcription Coactivator Activity
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Identical Protein Binding
Chromatin Binding
Protein Binding
Enzyme Binding
Poly(A) RNA Binding
Protein Heterodimerization Activity
Biological Process
Transcription, DNA-templated
L-phenylalanine Catabolic Process
Tetrahydrobiopterin Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Protein Homodimerization Activity
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Remodeling
DNA-templated Transcription, Elongation
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Cell Cycle
Response To Organic Substance
Gene Expression
Viral Process
Positive Regulation Of Macroautophagy
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Pathways
Phenylalanine and tyrosine catabolism
Metabolism of amino acids and derivatives
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
mRNA Capping
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
49 interactors:
ACIN1
APP
BRD7
CACNA1C
CALCOCO1
CDK5RAP2
CEBPZ
DENND4A
DIP2C
DVL2
DYRK1B
EHMT1
FXR2
GORASP2
GTF3C3
HES4
HNF1A
HNF1B
HNF4A
KLF13
LNX1
MIS18BP1
NFKB1
NIF3L1
NUDT18
PAH
PAPOLG
PCBD2
POLR3A
RBL2
RPS24
SAP30
SCMH1
SMARCD1
SOWAHC
SUPT5H
TFF3
TIMELESS
TRIM5
WDYHV1
WWP1
ZBTB25
ZNF195
ZNF202
ZNF23
ZNF263
ZNF451
ZNF567
ZNF714
37 interactors:
C9orf78
CCNH
CCNT1
CCNT2
CDK7
CDK9
CSNK2A1
DBN1
DCAF6
GTF3C1
H2AFX
HTATSF1
IK
IKBKG
LMAN2
MAML3
MNAT1
PCBD1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
SAP30BP
SIK1
SNX4
SSBP3
SUPT4H1
TERF1
XRCC5
ZBTB3
ZFYVE9
ZNF496
ZNF512B
Entrez ID
5092
6829
HPRD ID
00523
03655
Ensembl ID
ENSG00000166228
ENSG00000196235
Uniprot IDs
P61457
O00267
PDB IDs
2DO3
2E6Z
2E70
3H7H
4L1U
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Metabolic Process
Chromatin Remodeling
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Chromatin Organization
Insulin Secretion
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Chromosome Organization
Chromatin Modification
Endocrine Pancreas Development
Regulation Of Cellular Process
Peptide Hormone Secretion
Peptide Secretion
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Cellular Process
Positive Regulation Of DNA-templated Transcription, Initiation
Hormone Secretion
Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Viral Process
Transcription, DNA-templated
RNA Biosynthetic Process
DNA-templated Transcription, Elongation
Positive Regulation Of Viral Transcription
Viral Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Viral Transcription
Macromolecule Biosynthetic Process
Regulation Of Viral Process
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA-templated Transcription, Initiation
Biosynthetic Process
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Cell Cycle
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
7-methylguanosine MRNA Capping
7-methylguanosine RNA Capping
Transcription From RNA Polymerase II Promoter
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Metabolic Process
Cell Cycle
Cellular Metabolic Process
Nucleotide-excision Repair, DNA Damage Removal
Negative Regulation Of Gene Expression, Epigenetic
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Tagcloud
?
19q13
aa
acidic
argues
consensus
differ
end
family
homologue
lacks
like
map
maps
member
near
q
repeat
respond
ryanodine
seven
signals
similarity
spt5
spt6
terminus
unlike
w
yeast
Tagcloud (Difference)
?
19q13
aa
acidic
argues
consensus
differ
end
family
homologue
lacks
like
map
maps
member
near
q
repeat
respond
ryanodine
seven
signals
similarity
spt5
spt6
terminus
unlike
w
yeast
Tagcloud (Intersection)
?