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PCBD1 and PCBD2
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
PCBD1
PCBD2
Gene Name
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Cellular_component
Nucleus
Mitochondrion
Molecular Function
Transcription Coactivator Activity
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Identical Protein Binding
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Biological Process
Transcription, DNA-templated
L-phenylalanine Catabolic Process
Tetrahydrobiopterin Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Protein Homodimerization Activity
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Tetrahydrobiopterin Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Pathways
Phenylalanine and tyrosine catabolism
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Bulimia nervosa (
23568457
)
Colorectal cancer (
23263487
)
Height (
18391951
)
Protein-Protein Interactions
49 interactors:
ACIN1
APP
BRD7
CACNA1C
CALCOCO1
CDK5RAP2
CEBPZ
DENND4A
DIP2C
DVL2
DYRK1B
EHMT1
FXR2
GORASP2
GTF3C3
HES4
HNF1A
HNF1B
HNF4A
KLF13
LNX1
MIS18BP1
NFKB1
NIF3L1
NUDT18
PAH
PAPOLG
PCBD2
POLR3A
RBL2
RPS24
SAP30
SCMH1
SMARCD1
SOWAHC
SUPT5H
TFF3
TIMELESS
TRIM5
WDYHV1
WWP1
ZBTB25
ZNF195
ZNF202
ZNF23
ZNF263
ZNF451
ZNF567
ZNF714
31 interactors:
AATF
APP
ASCC2
BRF1
C1D
CDC5L
CENPK
CHAF1A
GTF2E1
HES4
IRF2BP1
KCNIP3
MAGEA11
MED21
MED30
MED4
MED7
MET
PBXIP1
PCBD1
PHF14
PML
RUNX1T1
SNW1
SSX3
SSX5
STAT3
TAL2
TGIF2LY
XBP1
ZZZ3
Entrez ID
5092
84105
HPRD ID
00523
17824
Ensembl ID
ENSG00000166228
Uniprot IDs
P61457
Q9H0N5
PDB IDs
4C45
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Metabolic Process
Chromatin Remodeling
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Chromatin Organization
Insulin Secretion
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Chromosome Organization
Chromatin Modification
Endocrine Pancreas Development
Regulation Of Cellular Process
Peptide Hormone Secretion
Peptide Secretion
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Cellular Process
Positive Regulation Of DNA-templated Transcription, Initiation
Hormone Secretion
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Apoptotic Process
Negative Regulation Of Gene Expression
Programmed Cell Death
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Cell Death
Death
Stem Cell Maintenance
Transcription From RNA Polymerase II Promoter
Cell Differentiation
Positive Regulation Of Histone Modification
Negative Regulation Of Cell Differentiation
Stem Cell Development
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Differentiation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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