PCBD1 and SOWAHC

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PCBD1	SOWAHC
Gene Name		pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	sosondowah ankyrin repeat domain family member C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Transcription, DNA-templated L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Homodimerization Activity Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		49 interactors: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WDYHV1 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF714	2 interactors: LIG4 PCBD1
Entrez ID		5092	65124
HPRD ID		00523	08643
Ensembl ID		ENSG00000166228	ENSG00000198142
Uniprot IDs		P61457	Q53LP3
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Metabolic Process Chromatin Remodeling Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Organization Insulin Secretion Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Chromatin Modification Endocrine Pancreas Development Regulation Of Cellular Process Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Process Positive Regulation Of DNA-templated Transcription, Initiation Hormone Secretion	DNA Ligation Involved In DNA Recombination Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Immunoglobulin V(D)J Recombination Tetrahydrobiopterin Biosynthetic Process DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation L-phenylalanine Catabolic Process L-phenylalanine Metabolic Process DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Regulation Of Protein Homodimerization Activity Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Pteridine-containing Compound Biosynthetic Process Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Aromatic Amino Acid Family Metabolic Process B Cell Activation Involved In Immune Response Response To Gamma Radiation Neuron Apoptotic Process Pteridine-containing Compound Metabolic Process Immunoglobulin Production Positive Regulation Of Fibroblast Proliferation Neuron Death T Cell Differentiation In Thymus Protein Homotetramerization Somatic Stem Cell Maintenance Nucleotide-excision Repair Regulation Of Fibroblast Proliferation Protein Tetramerization DNA-dependent DNA Replication DNA Biosynthetic Process Cellular Amino Acid Catabolic Process Cellular Response To Metal Ion Protein Heterooligomerization Cellular Response To Inorganic Substance Response To Ionizing Radiation Regulation Of Protein Binding
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