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PCBD1 and NUDT18
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PCBD1
NUDT18
Gene Name
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
nudix (nucleoside diphosphate linked moiety X)-type motif 18
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Cytosol
Molecular Function
Transcription Coactivator Activity
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Identical Protein Binding
Magnesium Ion Binding
Protein Binding
8-oxo-dGDP Phosphatase Activity
8-oxo-GDP Phosphatase Activity
8-hydroxy-dADP Phosphatase Activity
Biological Process
Transcription, DNA-templated
L-phenylalanine Catabolic Process
Tetrahydrobiopterin Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Protein Homodimerization Activity
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Nucleobase-containing Small Molecule Catabolic Process
Small Molecule Metabolic Process
DADP Catabolic Process
DGDP Catabolic Process
GDP Catabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Pathways
Phenylalanine and tyrosine catabolism
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
49 interactors:
ACIN1
APP
BRD7
CACNA1C
CALCOCO1
CDK5RAP2
CEBPZ
DENND4A
DIP2C
DVL2
DYRK1B
EHMT1
FXR2
GORASP2
GTF3C3
HES4
HNF1A
HNF1B
HNF4A
KLF13
LNX1
MIS18BP1
NFKB1
NIF3L1
NUDT18
PAH
PAPOLG
PCBD2
POLR3A
RBL2
RPS24
SAP30
SCMH1
SMARCD1
SOWAHC
SUPT5H
TFF3
TIMELESS
TRIM5
WDYHV1
WWP1
ZBTB25
ZNF195
ZNF202
ZNF23
ZNF263
ZNF451
ZNF567
ZNF714
34 interactors:
APIP
COIL
CUTC
DCTD
DHPS
DUT
EVI5L
GLUL
GNMT
GSE1
HSD17B14
KCTD13
KCTD17
KHDRBS3
KRT15
KRTAP4-12
KXD1
NADK
NAT9
NT5C2
PAICS
PCBD1
PSME3
RAB3IL1
RABAC1
RAD54B
RWDD1
SDPR
TARBP2
TERF2IP
TIFA
TRAF2
TRIM37
ZBED1
Entrez ID
5092
79873
HPRD ID
00523
07992
Ensembl ID
ENSG00000166228
Uniprot IDs
P61457
Q6ZVK8
PDB IDs
3GG6
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Metabolic Process
Chromatin Remodeling
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Chromatin Organization
Insulin Secretion
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Chromosome Organization
Chromatin Modification
Endocrine Pancreas Development
Regulation Of Cellular Process
Peptide Hormone Secretion
Peptide Secretion
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Cellular Process
Positive Regulation Of DNA-templated Transcription, Initiation
Hormone Secretion
Protein Homooligomerization
Protein Oligomerization
Nucleoside Metabolic Process
Protein Tetramerization
Nucleobase-containing Small Molecule Metabolic Process
Protein Complex Assembly
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Protein Homotetramerization
Nitrogen Compound Metabolic Process
Catabolic Process
Small Molecule Metabolic Process
S-adenosylmethionine Metabolic Process
Purine Nucleoside Metabolic Process
Methionine Metabolic Process
Regulation Of Protein Homodimerization Activity
IMP Metabolic Process
Alpha-amino Acid Metabolic Process
Nucleotide Biosynthetic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide Metabolic Process
Polyamine Metabolic Process
Cofactor Metabolic Process
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Protein Autoubiquitination
Purine Nucleobase Metabolic Process
Sulfur Amino Acid Metabolic Process
DUMP Biosynthetic Process
Deoxyhypusine Biosynthetic Process From Spermidine
DUTP Catabolic Process
Negative Regulation Of DNA Recombination At Telomere
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Pyrimidine Nucleoside Biosynthetic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Amino Acid Metabolic Process
I-kappaB Kinase/NF-kappaB Signaling
Glutamine Biosynthetic Process
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Spermidine Catabolic Process
L-methionine Biosynthetic Process From S-adenosylmethionine
Cellular Modified Amino Acid Metabolic Process
Pyrimidine Nucleotide Metabolic Process
Pyrimidine Nucleoside Metabolic Process
Targeting Of MRNA For Destruction Involved In RNA Interference
DUMP Metabolic Process
NADP Biosynthetic Process
DUTP Metabolic Process
Negative Regulation Of Cilium Assembly
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Tagcloud (Intersection)
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