PCBD1 and MIS18BP1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PCBD1	MIS18BP1
Gene Name		pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	MIS18 binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome	Chromosome, Centromeric Region Nucleoplasm
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Transcription, DNA-templated L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Homodimerization Activity Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process	Nucleosome Assembly Mitotic Nuclear Division CENP-A Containing Nucleosome Assembly Cell Division
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives	Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		49 interactors: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WDYHV1 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF714	2 interactors: PCBD1 SP1
Entrez ID		5092	55320
HPRD ID		00523	12629
Ensembl ID		ENSG00000166228	ENSG00000129534
Uniprot IDs		P61457	Q6P0N0
PDB IDs			1WGX
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Metabolic Process Chromatin Remodeling Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Organization Insulin Secretion Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Chromatin Modification Endocrine Pancreas Development Regulation Of Cellular Process Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Process Positive Regulation Of DNA-templated Transcription, Initiation Hormone Secretion	Sequestering Of Nodal From Receptor Via Nodal Binding Negative Regulation Of Nodal Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm Regulation Of Nodal Signaling Pathway Sequestering Of Extracellular Ligand From Receptor Negative Regulation Of Activin Receptor Signaling Pathway Tetrahydrobiopterin Biosynthetic Process Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy L-phenylalanine Catabolic Process L-phenylalanine Metabolic Process Lateral Mesoderm Development Enucleate Erythrocyte Differentiation Extracellular Negative Regulation Of Signal Transduction Regulation Of Protein Homodimerization Activity Atrial Septum Development Megakaryocyte Differentiation Regulation Of Activin Receptor Signaling Pathway Definitive Hemopoiesis Trophectodermal Cell Differentiation Interaction With Symbiont Pteridine-containing Compound Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Blastocyst Formation Embryonic Camera-type Eye Morphogenesis Negative Regulation Of BMP Signaling Pathway Aromatic Amino Acid Family Metabolic Process Embryonic Eye Morphogenesis Positive Regulation Of Viral Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Ventricular Septum Development Positive Regulation Of Cellular Biosynthetic Process Pteridine-containing Compound Metabolic Process Embryonic Camera-type Eye Development Determination Of Heart Left/right Asymmetry Protein Homotetramerization Regulation Of Viral Transcription Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Viral Process Cardiac Septum Development Regulation Of BMP Signaling Pathway Blastocyst Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Tetramerization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Erythrocyte Differentiation Negative Regulation Of Cellular Response To Growth Factor Stimulus Cardiac Ventricle Development Determination Of Left/right Symmetry
Tagcloud ?			alleviation assembly attachment canonical cdk cdk1 cdk2 cenp centromere centromeres coupling division ensures epigenetically exit hsknl2 initiating kept machinery microtubules mitosis mitotic noncentromeric nucleosomes poised propagation tight trigger uncoupled
Tagcloud (Difference) ?			alleviation assembly attachment canonical cdk cdk1 cdk2 cenp centromere centromeres coupling division ensures epigenetically exit hsknl2 initiating kept machinery microtubules mitosis mitotic noncentromeric nucleosomes poised propagation tight trigger uncoupled
Tagcloud (Intersection) ?