PCBD1 and CALCOCO1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PCBD1	CALCOCO1
Gene Name		pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	calcium binding and coiled-coil domain 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome	Nuclear Chromatin Nucleus Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Chromatin Binding Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Armadillo Repeat Domain Binding
	Biological Process	Transcription, DNA-templated L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Homodimerization Activity Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process	Transcription, DNA-templated Signal Transduction Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Panic disorder ( 19165232)
Protein-Protein Interactions		49 interactors: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WDYHV1 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF714	26 interactors: APP APTX CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 EP300 FAM161A FOSL1 GABARAPL2 GRIK2 HIST1H3A HIST1H4A IPP ISOC1 KRT15 MAPK1 NDC80 NEDD4 PCBD1 SH3GL3 TBC1D15 TBC1D17
Entrez ID		5092	57658
HPRD ID		00523	13868
Ensembl ID		ENSG00000166228	ENSG00000012822
Uniprot IDs		P61457	Q9P1Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Metabolic Process Chromatin Remodeling Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Organization Insulin Secretion Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Chromatin Modification Endocrine Pancreas Development Regulation Of Cellular Process Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Process Positive Regulation Of DNA-templated Transcription, Initiation Hormone Secretion	N-terminal Peptidyl-lysine Acetylation Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress DNA Replication-dependent Nucleosome Assembly Cellular Response To Heat N-terminal Protein Amino Acid Acetylation DNA Methylation On Cytosine Chromatin Silencing At RDNA Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Protein Stability N-terminal Protein Amino Acid Modification Notch Signaling Pathway Vesicle-mediated Transport Regulation Of Protein Binding Establishment Of Localization In Cell Intracellular Transport Response To Abiotic Stimulus Chromatin Silencing Placenta Blood Vessel Development Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Signal Transduction Response To Temperature Stimulus Positive Regulation Of Metabolic Process Response To Stress Posttranscriptional Regulation Of Gene Expression Histone H2B Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Neuromuscular Junction Development Regulation Of Metabolic Process Neuron Apoptotic Process Defense Response Cellular Localization Glutamate Receptor Signaling Pathway DNA Methylation Cellular Component Assembly Regulation Of Signaling Viral Process Neuron Death MAPK Import Into Nucleus Synaptic Growth At Neuromuscular Junction Polynucleotide 3' Dephosphorylation Vitellogenesis Regulation Of Binding Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Programmed Cell Death
Tagcloud ?			americans arg12his carm1 cataloging coding corepressor crebbp ep300 estrogens ethnic foxa1 hawaiians his52arg latinos mpg multiethnic ncoa1 ncoa2 ncoa3 ncor1 ncor2 nme1 nominally pparbp prmt1 smarca2 smarca4 steroid synonymous
Tagcloud (Difference) ?			americans arg12his carm1 cataloging coding corepressor crebbp ep300 estrogens ethnic foxa1 hawaiians his52arg latinos mpg multiethnic ncoa1 ncoa2 ncoa3 ncor1 ncor2 nme1 nominally pparbp prmt1 smarca2 smarca4 steroid synonymous
Tagcloud (Intersection) ?