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SUPT5H and ZFYVE9
Number of citations of the paper that reports this interaction (PubMedID
15231748
)
54
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SUPT5H
ZFYVE9
Description
SPT5 homolog, DSIF elongation factor subunit
zinc finger FYVE-type containing 9
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
DSIF Complex
Cytoplasm
Endosome
Early Endosome
Cytosol
Membrane
Early Endosome Membrane
Protein-containing Complex
Molecular Function
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
Protein Binding
1-phosphatidylinositol Binding
Zinc Ion Binding
Protein Domain Specific Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA-templated Transcription Elongation
Regulation Of Transcription By RNA Polymerase II
Transcription Elongation By RNA Polymerase II
Positive Regulation Of Macroautophagy
Regulation Of DNA-templated Transcription Elongation
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Regulation Of Transcription Elongation By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Endocytosis
Transforming Growth Factor Beta Receptor Signaling Pathway
Endosomal Transport
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
RNA Polymerase II Transcription Elongation
RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Hip circumference adjusted for BMI (
34021172
)
Interacting Genes
51 interacting genes:
C9orf78
CCNH
CCNT2
CDK7
CDK9
CEP55
CPSF7
CSNK2A1
DBN1
DCAF6
DSCAM
EXOSC7
FHL3
GOLGA2
GTF3C1
H2AX
HSPB1
HTATSF1
IK
IKBKG
LMAN2
MAD1L1
MAML3
MNAT1
PCBD1
PGK1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
RPL9
SAP30BP
SIK1
SNRNP48
SNX4
SSBP3
SUMO2
SUPT4H1
TERF1
TEX11
TLE5
XRCC5
YBX2
ZBTB3
ZFYVE9
ZNF496
ZNF512B
38 interacting genes:
ANKLE2
BAG6
BMP4
CHD6
CLTC
CTNNB1
DAZAP2
EIF4G1
ERBIN
ETS2
FHL2
JUP
LRP12
NIT1
NUP155
PML
PPP1CA
PPP1CB
PPP1CC
PPP2R1A
RBBP6
RHOT2
RNF11
RNPEP
SCYL2
SMAD2
SMAD3
SPART
ST7
SUMF2
SUPT5H
SVEP1
TENT5A
TGFBR1
TGFBR2
UBC
UBXN11
ZMYND8
Entrez ID
6829
9372
HPRD ID
03655
04782
Ensembl ID
ENSG00000196235
ENSG00000157077
Uniprot IDs
O00267
O95405
PDB IDs
2DO3
2E6Z
2E70
3H7H
4L1U
5OHO
5OHQ
5OIK
5U98
6EQY
6ER0
6GMH
6GML
6TED
7OKX
7OKY
7OL0
7PKS
7UNC
7UND
7YCX
8A3Y
8P4C
8P4D
8P4E
8P4F
8RBX
8UHA
8UHD
8UHG
8UI0
8UIS
8W8E
8W8F
9EGX
9EGY
9EGZ
9EH0
9EH2
9J0N
9J0O
9J0P
1DEV
1MK2
4BKW
5MJY
Enriched GO Terms of Interacting Partners
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Nucleus
Nucleic Acid Metabolic Process
Transcription Factor TFIIK Complex
CAK-ERCC2 Complex
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Cycle Process
Regulation Of Primary Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
DNA-templated Transcription Initiation
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Macromolecule Metabolic Process
Transcription Factor TFIIH Core Complex
Transcription Factor TFIIH Holo Complex
Nucleobase-containing Compound Biosynthetic Process
Regulation Of Gene Expression
Transcription Elongation By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Regulation Of Mitotic Cell Cycle
Protein Localization To Chromosome
Regulation Of Macromolecule Metabolic Process
DNA-templated Transcription Elongation
Protein Peptidyl-prolyl Isomerization
Chromosome
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of DNA-templated Transcription, Elongation
Regulation Of Chromosome Segregation
DNA Metabolic Process
Recombinational Repair
Protein Localization To Site Of Double-strand Break
Protein Binding
DNA Recombination
Transcription Pausing By RNA Polymerase II
Postsynaptic Cytosol
Histone H4R3 Methyltransferase Activity
Peptidyl-arginine Methylation
DNA Repair
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Anoikis
Regulation Of Transcription Elongation By RNA Polymerase II
Transcription Elongation-coupled Chromatin Remodeling
Macromolecule Biosynthetic Process
Embryonic Cranial Skeleton Morphogenesis
Positive Regulation Of Epithelial To Mesenchymal Transition
Ubiquitin Protein Ligase Binding
Embryonic Skeletal System Morphogenesis
I-SMAD Binding
SMAD Binding
Lung Development
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Regulation Of Epithelial To Mesenchymal Transition
Skeletal System Morphogenesis
Entrainment Of Circadian Clock By Photoperiod
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Signal Transduction
Trachea Formation
Trophoblast Cell Migration
PTW/PP1 Phosphatase Complex
Embryonic Organ Morphogenesis
Photoperiodism
Entrainment Of Circadian Clock
Activin Receptor Signaling Pathway
Embryonic Foregut Morphogenesis
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Cell Fate Commitment
Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tissue Development
Gastrulation
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Branching Involved In Lung Morphogenesis
Tube Morphogenesis
Positive Regulation Of Developmental Process
Regulation Of Chondrocyte Differentiation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Mesenchyme Development
Regulation Of Developmental Process
Formation Of Primary Germ Layer
Branching Morphogenesis Of An Epithelial Tube
Osteoblast Differentiation
Bronchus Development
Animal Organ Formation
Positive Regulation Of DNA-templated Transcription, Elongation
Catenin-TCF7L2 Complex
Paraxial Mesoderm Morphogenesis
Transforming Growth Factor Beta Ligand-receptor Complex
Regulation Of Translation In Response To Stress
Circadian Regulation Of Gene Expression
In Utero Embryonic Development
Regulation Of SMAD Protein Signal Transduction
Developmental Growth
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