DEF6 and ZAP70

  • Number of citations of the paper that reports this interaction (PMID 12648457)
  • 24
  • Data Source:
  • HPRD (in vivo, in vitro)

DEF6

ZAP70

Gene Name differentially expressed in FDCP 6 homolog (mouse) zeta-chain (TCR) associated protein kinase 70kDa
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 15 interactors: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70 58 interactors: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP VAV1 WIPF1
Entrez ID 50619 7535
HPRD ID 10869 01495
Ensembl ID ENSG00000023892 ENSG00000115085
Uniprot IDs Q9H4E7 P43403
PDB IDs 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
Tagcloud (Difference) ?
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
Tagcloud (Intersection) ?