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DEF6 and BEGAIN
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
DEF6
BEGAIN
Gene Name
differentially expressed in FDCP 6 homolog (mouse)
brain-enriched guanylate kinase-associated
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Cell-cell Junction
Membrane
Cytoplasm
Membrane
Dendrite
Neuronal Cell Body
Molecular Function
Protein Binding
Biological Process
Pathways
Drugs
Diseases
GWAS
Height (
18391951
)
Menarche (age at onset) (
21102462
)
Protein-Protein Interactions
15 interactors:
APP
BEGAIN
CDC42
CDC42EP1
EIF4ENIF1
HOMEZ
LCK
PBXIP1
PLSCR1
PTK2
RAC1
RAC2
RHOA
TCF4
ZAP70
23 interactors:
ABLIM1
APP
BAHD1
CATSPER1
DEF6
DLG1
DLG4
DTNB
ENKD1
FAM107A
GFI1B
HGS
HID1
KIAA0408
QSOX1
RBL1
RIBC2
TRIM27
USP2
ZFP64
ZNF250
ZNF417
ZNF774
Entrez ID
50619
57596
HPRD ID
10869
06459
Ensembl ID
ENSG00000023892
ENSG00000183092
Uniprot IDs
Q9H4E7
Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners
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Platelet Activation
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Regulation Of Signal Transduction
Axon Guidance
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Regulation Of Cell Morphogenesis
Locomotion
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Projection Organization
Response To External Stimulus
Ephrin Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Axonogenesis
Positive Regulation Of Immune System Process
Positive Regulation Of Cell Projection Organization
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Axon Development
Regulation Of Cell Projection Assembly
Cell Morphogenesis Involved In Neuron Differentiation
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cellular Component Biogenesis
Chemotaxis
Regulation Of Cell Adhesion
Regulation Of Cell Differentiation
Neuron Projection Morphogenesis
Positive Regulation Of Immune Response
Peptidyl-tyrosine Autophosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell-cell Adhesion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of Signal Transduction
Cell Differentiation
Innate Immune Response
Regulation Of Cell-substrate Adhesion
Neuron Projection Development
Response To Stress
Regulation Of Immune System Process
Regulation Of Lipid Kinase Activity
Cell Migration
Receptor Localization To Synapse
Regulation Of Metabolic Process
Protein Localization To Synapse
Regulation Of Gene Expression
Cell Recognition
Regulation Of Transcription, DNA-templated
Regulation Of Cellular Process
Cortical Actin Cytoskeleton Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Establishment Or Maintenance Of Apical/basal Cell Polarity
Axon Guidance
Cortical Cytoskeleton Organization
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ion Transmembrane Transport
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Receptor Clustering
Axonogenesis
Response To Brefeldin A
Locomotory Behavior
Gene Expression
Negative Regulation Of Cellular Metabolic Process
Nucleotide Phosphorylation
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Cell-cell Recognition
Chemotaxis
Regulation Of Membrane Potential
Regulation Of Ion Transport
Negative Regulation Of Transcription, DNA-templated
Neuron Projection Morphogenesis
Negative Regulation Of Interleukin-2 Secretion
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Nitrogen Compound Metabolic Process
Neuromuscular Process Controlling Balance
Synapse Assembly
Negative Regulation Of RNA Biosynthetic Process
Regulation Of ERBB Signaling Pathway
Collateral Sprouting In Absence Of Injury
Cell Morphogenesis Involved In Differentiation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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