DEF6 and EIF4ENIF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DEF6	EIF4ENIF1
Gene Name		differentially expressed in FDCP 6 homolog (mouse)	eukaryotic translation initiation factor 4E nuclear import factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Membrane	Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function		Protein Binding Protein Transporter Activity Poly(A) RNA Binding
	Biological Process		Protein Transport
Pathways
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		15 interactors: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70	19 interactors: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 MGAT5B OIP5 SMAD3 SPAG5 TTC19 TXLNA
Entrez ID		50619	56478
HPRD ID		10869	10456
Ensembl ID		ENSG00000023892	ENSG00000184708
Uniprot IDs		Q9H4E7	Q9NRA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Regulation Of Signal Transduction Axon Guidance Regulation Of Signaling Regulation Of Intracellular Signal Transduction Regulation Of Cell Morphogenesis Locomotion Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Projection Organization Response To External Stimulus Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Immune System Process Positive Regulation Of Cell Projection Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Axon Development Regulation Of Cell Projection Assembly Cell Morphogenesis Involved In Neuron Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cellular Component Biogenesis Chemotaxis Regulation Of Cell Adhesion Regulation Of Cell Differentiation Neuron Projection Morphogenesis Positive Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Signal Transduction Cell Differentiation Innate Immune Response Regulation Of Cell-substrate Adhesion Neuron Projection Development Response To Stress Regulation Of Immune System Process Regulation Of Lipid Kinase Activity Cell Migration	Cellular Macromolecular Complex Assembly Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cell Division RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cell Cycle Negative Regulation Of Osteoblast Differentiation Translational Initiation MRNA Metabolic Process Positive Regulation Of Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Viral Process Cell Dedifferentiation Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Regulation Of Translation Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Negative Regulation Of Ossification Mitotic Cell Cycle Process Negative Regulation Of Translation Evasion Or Tolerance Of Host Defenses By Virus Mitotic Cell Cycle Cellular Component Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Farnesyl Diphosphate Metabolic Process Regulation Of Cell-matrix Adhesion Lymphocyte Activation Positive Regulation Of Cell-substrate Adhesion Regulation Of Extracellular Matrix Assembly Nuclear Export
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