ZAP70 and LCP2

  • Number of citations of the paper that reports this interaction (PMID 8702662)
  • 66
  • Data Source:
  • HPRD (in vitro, in vivo)

ZAP70

LCP2

Gene Name zeta-chain (TCR) associated protein kinase 70kDa lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 58 interactors: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP VAV1 WIPF1 39 interactors: APP BLNK CBL CD22 CLNK FXR2 FYB FYN GOLGA2 GRAP2 GRB2 HCK ITK LAT LCK LYN MAP4K1 NCK1 NCK2 PAG1 PIK3R1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAZ ZAP70
Entrez ID 7535 3937
HPRD ID 01495 03362
Ensembl ID ENSG00000115085
Uniprot IDs P43403 Q13094
PDB IDs 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R 1H3H 1YWO 2EAP 2ROR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3  zap70 
Tagcloud (Difference) ?
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3 
Tagcloud (Intersection) ?
zap70