SNAP29 and STX12

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SNAP29	STX12
Description		synaptosome associated protein 29	syntaxin 12
Image
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse	Golgi Membrane Phagophore Assembly Site Nucleoplasm Endosome Golgi Apparatus Synaptic Vesicle Endosome Membrane Endomembrane System Membrane Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Cytoplasmic Vesicle Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Endocytic Recycling Cholesterol Efflux Vesicle Docking Protein Stabilization Regulation Of Biological Quality
Pathways		Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS
Interacting Genes		24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7	44 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FAM209A FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A1 SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		9342	23673
HPRD ID		11968	06059
Ensembl ID		ENSG00000099940	ENSG00000117758
Uniprot IDs		O95721	Q86Y82
PDB IDs		4WY4 7BV6	2DNX
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	Membrane SNARE Complex Exocytosis Membrane Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane SNAP Receptor Activity Membrane Organization Secretion By Cell Synaptic Vesicle Membrane Organization Synaptic Vesicle Priming Vesicle-mediated Transport Vesicle Fusion Syntaxin Binding Organelle Membrane Fusion Secretion Organelle Fusion Organelle Localization By Membrane Tethering Membrane Docking Synaptic Vesicle Docking Vesicle Organization Vesicle Docking Establishment Of Localization In Cell Organelle Localization SNARE Binding Protein Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Presynaptic Active Zone Membrane Signal Release Bile Acid:sodium Symporter Activity Cellular Localization Synaptic Vesicle Exocytosis Vesicle-mediated Transport In Synapse Mitochondrial Membrane ATP-dependent Protein Binding Regulated Exocytosis Vesicle Docking Involved In Exocytosis Ammonium Channel Activity Cytoplasmic Vesicle Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Presynapse Regulation Of Synaptic Vesicle Priming Water Channel Activity Tertiary Granule Membrane Intracellular Transport BLOC-1 Complex Vesicle Targeting Somatodendritic Compartment
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