SNAP29 and VAMP7

Number of citations: 39 (PubMedID 12853575)
Data Source: HPRD (in vivo, two hybrid)

		SNAP29	VAMP7
Name		synaptosome associated protein 29	vesicle associated membrane protein 7
Structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse	Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Endomembrane System Membrane Lamellipodium Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Clathrin-coated Endocytic Vesicle Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Cytoplasmic Vesicle Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Synapse Phagocytic Vesicle Extracellular Exosome Plasma Membrane Bounded Cell Projection
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation	Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Autophagosome Maturation Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		Neutrophil degranulation Intra-Golgi traffic	trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Interleukin-12 signaling
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7	12 interacting genes: AGFG1 ANKRD27 AP3D1 CALM1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7
Entrez ID		9342	6845
HPRD ID		11968	02084
Ensembl ID		ENSG00000099940	ENSG00000124333
Uniprot IDs		O95721	P51809
PDB IDs		4WY4 7BV6	2DMW
GO Terms Enriched among Interactors		SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering Vesicle Organization Membrane Docking Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport SNARE Binding Membrane Fusion Vesicle-mediated Transport In Synapse Exocytosis Establishment Of Localization In Cell Organelle Localization Synaptic Vesicle Membrane Organization Vesicle Docking Membrane Organization Secretion By Cell Secretion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Azurophil Granule Long-term Synaptic Potentiation Neuron Projection Protein Transport Specific Granule Synaptic Vesicle Priming Presynapse Establishment Of Protein Localization Neurotransmitter Transport Endomembrane System Synaptic Vesicle Exocytosis Synaptic Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Signal Release Intracellular Transport Intracellular Protein Localization Organelle Organization Syntaxin Binding Regulation Of Synaptic Plasticity Autophagosome Membrane Docking ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Cytoplasmic Vesicle Modulation Of Chemical Synaptic Transmission Voltage-gated Potassium Channel Complex Intracellular Protein Transport Endosome To Melanosome Transport