SNAP29 and TXNRD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNAP29	TXNRD3
Description		synaptosome associated protein 29	thioredoxin reductase 3
Image
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Thioredoxin-disulfide Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, NAD(P) As Acceptor Flavin Adenine Dinucleotide Binding
	Biological Process	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation	Spermatogenesis Cell Differentiation Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways		Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS
Interacting Genes		24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7	9 interacting genes: ANKRD36B BOLA1 BOLA2 BOLA2B CINP CTNNA3 FHL2 PACRGL SNAP29
Entrez ID		9342	114112
HPRD ID		11968
Ensembl ID		ENSG00000099940	ENSG00000197763
Uniprot IDs		O95721	B4DRZ5 Q86VQ6
PDB IDs		4WY4 7BV6	3H8Q
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	Iron-sulfur Cluster Assembly Complex Iron-sulfur Cluster Assembly Cell Redox Homeostasis Intracellular Iron Ion Homeostasis [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Binding Atrial Cardiac Muscle Cell Development Inorganic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Intracellular Monoatomic Cation Homeostasis Ciliary Pocket Membrane Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Intracellular Chemical Homeostasis Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Autophagosome Membrane Docking Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Cellular Homeostasis Fascia Adherens Preribosome Binding Ventricular Cardiac Muscle Cell Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
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