MBNL1 and ABI3BP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MBNL1	ABI3BP
Description		muscleblind like splicing regulator 1	ABI family member 3 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Extracellular Matrix Structural Constituent
	Biological Process	In Utero Embryonic Development MRNA Processing Nervous System Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Blond vs. brown/black hair color ( 30531825) End-stage renal disease ( 29885931) Fasting glucose ( 34059833) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Infantile hypertrophic pyloric stenosis ( 22306654) Liver enzyme levels (alanine transaminase) ( 33972514) Male-pattern baldness ( 27182965) Prostate cancer ( 29892016) Type 2 diabetes ( 30054458 30297969 32499647) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) White blood cell count ( 32888494)	Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Alcohol dependence ( 26365420) Asthma (childhood onset) ( 23829686) Carotid plaque burden ( 28282560) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Joint mobility (Beighton score) ( 27182965) Multiple sclerosis ( 31604244) Optic disc area ( 25631615 28073927) Optic disc size ( 31809533) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		21 interacting genes: ABI3BP AEN APP BCAS2 BIN1 CEBPA DAB1 DMRTB1 FBXO7 IDH3A ITSN2 PKM PRPF39 QKI RBFOX2 RBPMS RPL21 SNRPA TLE5 UBC ZNHIT3	6 interacting genes: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1
Entrez ID		4154	25890
HPRD ID		07355	09380
Ensembl ID		ENSG00000152601	ENSG00000154175
Uniprot IDs		A0A0A0MQX8 C9JP00 Q86VM6 Q9NR56	D3YTG3 F6R962 H7C556 Q7Z7G0
PDB IDs		3D2N 3D2Q 3D2S 5U6H 5U6L 5U9B
Enriched GO Terms of Interacting Partners?		Regulation Of Astrocyte Differentiation RNA Processing Nucleus RNA Splicing Regulation Of Glial Cell Differentiation Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of Gliogenesis MRNA Binding MRNA Processing U1 SnRNP Negative Regulation Of Cell Development Negative Regulation Of Blood Circulation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Hemopoiesis Positive Regulation Of Glial Cell Differentiation Synaptic Vesicle Endocytosis Lipid Tube Positive Regulation Of Developmental Process Negative Regulation Of Ventricular Cardiac Muscle Cell Action Potential Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway RNA Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Nucleic Acid Binding MRNA Metabolic Process Regulation Of MRNA Processing Internal N(7)-methylguanine-containing RNA Reader Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Presynaptic Endocytosis Vesicle Dendrite Development Macrophage Differentiation Regulation Of RNA Splicing Regulation Of Neuron Differentiation RNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Amyloid Precursor Protein Catabolic Process Lipid Tube Assembly Negative Regulation Of Cardiac Muscle Cell Contraction Negative Regulation Of Multicellular Organismal Process Acetylcholine Receptor Activator Activity Lipoprotein Particle	Branching Involved In Labyrinthine Layer Morphogenesis L-cysteine Transaminase Activity L-glutamate Catabolic Process To Aspartate L-aspartate:2-oxoglutarate Aminotransferase Activity Aspartate Biosynthetic Process Phosphatidylserine Decarboxylase Activity L-glutamate Biosynthetic Process Embryonic Morphogenesis Guanyl-nucleotide Exchange Factor Adaptor Activity Anatomical Structure Morphogenesis Grb2-EGFR Complex Oxaloacetate Metabolic Process Transdifferentiation Carboxylic Acid Binding L-aspartate Catabolic Process Glutamate Biosynthetic Process L-glutamate Catabolic Process Malate-aspartate Shuttle Response To Transition Metal Nanoparticle Glycerol Biosynthetic Process Negative Regulation Of Mitochondrial Depolarization Aspartate Metabolic Process Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Regulation Of Lymphocyte Mediated Immunity Neurotrophin TRKA Receptor Binding Chorionic Trophoblast Cell Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Intestinal Epithelial Cell Maturation Glandular Epithelial Cell Maturation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Spemann Organizer Formation Post-embryonic Camera-type Eye Development Male Pronucleus Actin-based Cell Projection Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Ruffle Assembly Regulation Of Cell Junction Assembly Anterior/posterior Axis Specification, Embryo Columnar/cuboidal Epithelial Cell Maturation Synapse Organization Female Pronucleus Defense Response To Tumor Cell Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Cytosolic Calcium Ion Concentration Glycerol Metabolic Process Cell Differentiation Morphogenesis Of An Epithelium Insulin Receptor Substrate Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
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