MBNL1 and BIN1

Number of citations of the paper that reports this interaction (PMID 21623381)
41

Data Source:
BioGRID (unspecified method)

		MBNL1	BIN1
Gene Name		muscleblind-like splicing regulator 1	bridging integrator 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytoplasmic Stress Granule	Nucleus Cytoplasm Synaptic Vesicle Actin Cytoskeleton Membrane Z Disc T-tubule Axon I Band Node Of Ranvier Axon Initial Segment Varicosity Axon Terminus Cerebellar Mossy Fiber Lipid Tube
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding	Protein Binding Protein Complex Binding Identical Protein Binding Protein Heterodimerization Activity Tau Protein Binding GTPase Binding RNA Polymerase Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Nervous System Development Skeletal Muscle Tissue Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation	Endocytosis Cell Proliferation Viral Process Muscle Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis Positive Regulation Of Astrocyte Differentiation Lipid Tube Assembly Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS		Infantile hypertrophic pyloric stenosis ( 22306654)	Alzheimer's disease ( 22832961 21460840 21627779 22005930) Alzheimer's disease (late onset) ( 21460841 21390209)
Protein-Protein Interactions		9 interactors: ABI3BP AEN AES APP BIN1 DAB1 IDH3A ITSN2 ZNHIT3	36 interactors: ABL1 AMPH AP2A1 AP2A2 APP ASAP2 ATXN2 CUX1 DLGAP4 DNM1 DNM2 FBP1 ITGA1 ITGA3 ITGA6 MAP4K3 MBNL1 MYC PLD1 PLD2 PTK2 RAP1A RFX3 RIN2 RIN3 SH3GL2 SH3GLB1 SNX4 SOS1 SOS2 SYN1 SYNJ1 TP73 UBC XRCC4 ZBTB3
Entrez ID		4154	274
HPRD ID		07355	03150
Ensembl ID		ENSG00000152601	ENSG00000136717
Uniprot IDs		Q86VM6 Q9NR56	B7Z6Y2 O00499 Q9BTH3
PDB IDs		3D2N 3D2Q 3D2S	1MUZ 1MV0 1MV3 2FIC 2RMY 2RND
Enriched GO Terms of Interacting Partners?		Regulation Of Astrocyte Differentiation Regulation Of Glial Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Regulation Of Gliogenesis Lipid Tube Assembly Cerebellum Structural Organization Synaptic Growth At Neuromuscular Junction Adult Locomotory Behavior Regulation Of Neuron Differentiation Collateral Sprouting In Absence Of Injury Lateral Motor Column Neuron Migration Dendrite Development Regulation Of Protein Binding Spinal Cord Motor Neuron Migration Positive Regulation Of Anoikis Endocytosis Positive Regulation Of Catalytic Activity Adult Behavior Radial Glia Guided Migration Of Purkinje Cell Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Neurogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Axon Choice Point Recognition Regulation Of Cell Development Locomotory Behavior Neuron Remodeling Positive Regulation Of Astrocyte Differentiation Regulation Of Binding	Regulation Of Signaling Endocytosis Generation Of Neurons Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Projection Organization Regulation Of ERBB Signaling Pathway Neurogenesis Neuron Projection Morphogenesis Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Signal Transduction Axon Guidance Neuron Differentiation Neuron Development Nervous System Development Vesicle-mediated Transport Chemotaxis Signaling Neuron Projection Development Locomotion Cell Communication Anatomical Structure Morphogenesis Cell Morphogenesis Axonogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axon Development Negative Regulation Of Signaling Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of ERBB Signaling Pathway Regulation Of Cellular Process Cell Development Positive Regulation Of Catalytic Activity Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway System Development Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Movement Of Cell Or Subcellular Component Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Positive Regulation Of Apoptotic Process Blood Coagulation
Tagcloud ?		arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator	a2m algorithm allele alzheimer amplicons apoe apoj biochip clut combinations cr1 determina e3 e4 epsilon2 epsilon4 exoc3l2 gab2 genotyping immobilized microchip oligonucleotides picalm predis rs11136000 sporadic studying tion tomm40
Tagcloud (Difference) ?		arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator	a2m algorithm allele alzheimer amplicons apoe apoj biochip clut combinations cr1 determina e3 e4 epsilon2 epsilon4 exoc3l2 gab2 genotyping immobilized microchip oligonucleotides picalm predis rs11136000 sporadic studying tion tomm40
Tagcloud (Intersection) ?