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MYH9 and GRIN1
Number of citations of the paper that reports this interaction (PMID
10862698
)
203
Data Source:
HPRD
(in vivo)
MYH9
GRIN1
Gene Name
myosin, heavy chain 9, non-muscle
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Image
Gene Ontology Annotations
Cellular Component
Stress Fiber
Ruffle
Immunological Synapse
Uropod
Nucleus
Cytoplasm
Spindle
Actomyosin Contractile Ring
Cytosol
Plasma Membrane
Cell-cell Adherens Junction
COP9 Signalosome
Integrin Complex
Actin Cytoskeleton
Membrane
Myosin II Complex
Cortical Cytoskeleton
Cell Leading Edge
Neuromuscular Junction
Cleavage Furrow
Actomyosin
Protein Complex
Extracellular Vesicular Exosome
Myosin II Filament
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Synaptic Vesicle
Cell Surface
Postsynaptic Density
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Dendrite Membrane
Neuron Projection
Synaptic Cleft
Terminal Bouton
Dendritic Spine
Synapse
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Molecular Function
Microfilament Motor Activity
Motor Activity
Actin Binding
Protein Binding
Calmodulin Binding
ATP Binding
ATPase Activity
Actin-dependent ATPase Activity
Protein Homodimerization Activity
Protein Anchor
ADP Binding
Poly(A) RNA Binding
Actin Filament Binding
N-methyl-D-aspartate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Glycine Binding
Glutamate Binding
Enzyme Binding
Voltage-gated Cation Channel Activity
Glutamate Receptor Binding
Neurotransmitter Binding
Protein Heterodimerization Activity
Biological Process
Meiotic Spindle Organization
Cytokinesis
Angiogenesis
In Utero Embryonic Development
Establishment Of T Cell Polarity
Membrane Protein Ectodomain Proteolysis
Integrin-mediated Signaling Pathway
Axon Guidance
Myoblast Fusion
Regulation Of Cell Shape
Protein Transport
Actin Filament-based Movement
Platelet Formation
Monocyte Differentiation
Actomyosin Structure Organization
Actin Cytoskeleton Reorganization
Uropod Organization
Termination Of G-protein Coupled Receptor Signaling Pathway
Blood Vessel Endothelial Cell Migration
Ephrin Receptor Signaling Pathway
Leukocyte Migration
Establishment Of Meiotic Spindle Localization
Platelet Aggregation
Conditioned Taste Aversion
Suckling Behavior
Response To Amphetamine
Cation Transport
Cellular Calcium Ion Homeostasis
Synaptic Transmission
Axon Guidance
Respiratory Gaseous Exchange
Long-term Memory
Adult Locomotory Behavior
Olfactory Learning
Visual Learning
Propylene Metabolic Process
Sensory Perception Of Pain
Pons Maturation
Cerebral Cortex Development
Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transport
Social Behavior
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Membrane Potential
Positive Regulation Of Apoptotic Process
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Respiratory Gaseous Exchange
Response To Ethanol
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Ephrin Receptor Signaling Pathway
Regulation Of Long-term Neuronal Synaptic Plasticity
Rhythmic Process
Regulation Of Dendrite Morphogenesis
Regulation Of Axonogenesis
Protein Tetramerization
Response To Calcium Ion
Regulation Of Synapse Assembly
Calcium Ion Homeostasis
Regulation Of Excitatory Postsynaptic Membrane Potential
Prepulse Inhibition
Male Mating Behavior
Response To Fungicide
Calcium Ion Transmembrane Transport
Cellular Response To Manganese Ion
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
EPHA-mediated growth cone collapse
Axon guidance
Semaphorin interactions
EPH-Ephrin signaling
Sema4D in semaphorin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Sema4D induced cell migration and growth-cone collapse
Innate Immune System
EPHB-mediated forward signaling
Axon guidance
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
EPH-Ephrin signaling
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Meperidine
Orphenadrine
Dcka, 5,7-Dichlorokynurenic Acid
D-Serine
Cycloleucine
Milnacipran
Agmatine
Diseases
GWAS
End-stage renal disease (non-diabetic) (
20532800
)
Glomerulosclerosis (
20668430
)
Optic disc size (rim) (
20395239
)
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Protein-Protein Interactions
22 interactors:
ASCC2
CASP4
CBL
CD163
CSNK2A1
CXCR4
GRB2
GRIN1
MEN1
MYBPC3
MYH10
MYL9
MYOM1
MYOM2
OVGP1
PPP2CA
PTPN6
RAC1
S100A4
TTN
TUFM
YWHAZ
53 interactors:
ACTN2
AKAP9
CALM1
CAMK2A
CAMK2G
CANX
CDH2
CIT
CLTC
CTNNB1
DLG2
DLG3
DLG4
DLGAP4
DNM1
DRD1
DUSP4
EPHB2
EPHB4
FUS
FYN
GRIN2A
GRIN2B
GRIN2D
GRIN3A
HNRNPU
HRAS
HSPA1A
INA
LNX1
LRP8
MAP2
MAP2K2
MYH9
NANOS1
NEFL
NF1
PLAT
PLCG1
PPP2R1A
PPP2R2A
PRKCA
PRKCB
PRKCE
PRKCG
RAP2A
RPS6KA3
SP3
SPTAN1
SYNGAP1
TJP1
TRAF3
TUBA4B
Entrez ID
4627
2902
HPRD ID
01177
15926
Ensembl ID
ENSG00000100345
ENSG00000176884
Uniprot IDs
P35579
Q05586
Q59GW0
Q5VSF9
PDB IDs
2LNK
3ZWH
4ETO
2HQW
2NR1
3BYA
Enriched GO Terms of Interacting Partners
?
Cell Morphogenesis Involved In Differentiation
Cell Development
Platelet Activation
Axon Guidance
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Morphogenesis
Movement Of Cell Or Subcellular Component
Anatomical Structure Morphogenesis
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Wound Healing
Chemotaxis
Locomotion
Positive Regulation Of Signal Transduction
Neuron Projection Morphogenesis
Apoptotic Process
Muscle Contraction
Cell Activation
Blood Coagulation
Programmed Cell Death
Hemostasis
Ephrin Receptor Signaling Pathway
Response To Wounding
Cell Death
Death
Muscle System Process
Neuron Projection Development
Cell Projection Morphogenesis
Myosin Filament Assembly
Cell Part Morphogenesis
Regulation Of Body Fluid Levels
Cell Differentiation
Neuron Development
Regulation Of Cellular Component Organization
Actin Filament-based Movement
Regulation Of Signaling
Cell Surface Receptor Signaling Pathway
Endomembrane System Organization
Neuron Differentiation
T Cell Costimulation
Myofibril Assembly
Leukocyte Migration
Brain Development
Cell Projection Organization
Regulation Of Kinase Activity
Head Development
Regulation Of Signal Transduction
Anatomical Structure Development
Synaptic Transmission
Cell-cell Signaling
Nervous System Development
Signaling
Locomotion
Cell Communication
Neurogenesis
Cell Differentiation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Organic Substance
Generation Of Neurons
Neuron Projection Development
Neuron Development
Developmental Process
Cell Development
Neuron Differentiation
Response To External Stimulus
Signal Transduction
Cell Projection Organization
Movement Of Cell Or Subcellular Component
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
System Development
Cellular Response To Stimulus
Anatomical Structure Development
Axon Development
Axon Guidance
Regulation Of Synaptic Transmission
Regulation Of Synaptic Plasticity
Neuron Projection Morphogenesis
Cell Surface Receptor Signaling Pathway
Axonogenesis
Cellular Response To Organic Substance
Response To Wounding
Cell Morphogenesis Involved In Neuron Differentiation
Cell Morphogenesis Involved In Differentiation
Learning
Response To Stimulus
Regulation Of Signaling
Chemotaxis
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Response To Abiotic Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Cell Projection Morphogenesis
Single-organism Behavior
Cellular Response To Growth Factor Stimulus
Learning Or Memory
Tagcloud
?
abundance
acetylation
attempt
capability
cognate
consolidate
coordinating
cytoplasmic
deacetylase
deacetylation
diversity
dnaj
dnaja1
elucidated
hdac6
homolog
hsc70
knockout
modulates
monitor
myosin
negatively
notion
participates
predominantly
proteomic
serves
subfamily
verified
Tagcloud (Difference)
?
abundance
acetylation
attempt
capability
cognate
consolidate
coordinating
cytoplasmic
deacetylase
deacetylation
diversity
dnaj
dnaja1
elucidated
hdac6
homolog
hsc70
knockout
modulates
monitor
myosin
negatively
notion
participates
predominantly
proteomic
serves
subfamily
verified
Tagcloud (Intersection)
?