Wiki-Pi
About
Search
People
Updates
Search
MCM7 and H3-4
Number of citations of the paper that reports this interaction (PubMedID
8798650
)
0
Data Source:
HPRD
(in vitro)
MCM7
H3-4
Description
minichromosome maintenance complex component 7
H3.4 histone, cluster member
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Membrane
MCM Complex
CMG Complex
Chromosome, Telomeric Region
Nucleosome
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Chromosome
Extracellular Exosome
Molecular Function
Nucleotide Binding
DNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Single-stranded DNA Helicase Activity
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Biological Process
Double-strand Break Repair Via Break-induced Replication
DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
DNA Damage Response
Cell Population Proliferation
Response To Xenobiotic Stimulus
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Phosphorylation
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Xenobiotic Stimulus
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Chromatin Assembly
Spermatogonial Cell Division
Regulation Of Cell Differentiation
Pathways
Activation of ATR in response to replication stress
Unwinding of DNA
Assembly of the pre-replicative complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
Condensation of Prophase Chromosomes
DNA Damage/Telomere Stress Induced Senescence
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Meiotic recombination
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
79 interacting genes:
ABI2
AK8
APP
ASB8
C8orf34
CCDC102B
CCND1
CCNH
CDC42
CDC45
CDC6
CDC7
CDK7
CDKN1B
CEBPA
CEP68
CHEK1
COG6
CRLS1
CRYAA
DBF4
DNAAF6
DUX4
ELOC
ESCO2
FHL2
GOLGA2
H3-4
HIF1A
IKBKG
IKZF3
INTS6
KIFC3
LINC01554
LNX2
LRR1
MAGEA6
MBIP
MCM10
MCM2
MCM3
MCM4
MCM5
MCM6
MCM8
MEOX2
MIPOL1
MNAT1
NAB2
NFKBIA
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
PLK1
PNMA1
RAD17
RB1
RBL1
RBL2
RBM8A
RBPMS
RINT1
RNF181
RPA1
SMC1A
SNTA1
SP2
SSX2IP
TFIP11
TREX1
TRIM27
TRIM54
TRIM63
UBE3A
UBQLN1
USHBP1
195 interacting genes:
ADNP
AFF1
AHDC1
ANP32A
ASF1A
ASH2L
ATAD2
AURKA
AURKB
BACC1
BIRC5
BMI1
BPTF
BRD7
CBX1
CBX2
CBX3
CBX4
CBX5
CBX7
CBX8
CDYL
CDYL2
CHAF1A
CHAF1B
CHAMP1
CHD1
CHD4
CHD6
CHUK
COPRS
CREBBP
CTBP1
CTBP2
DCAF1
DEK
DNMT1
DOT1L
DPF2
DPY30
DYRK2
EGFR
EHMT1
EHMT2
EMSY
EP300
ERAP1
EZH2
FOXA1
GADD45A
GATAD1
GLYR1
GTF3C4
HAT1
HDAC1
HDAC2
HDAC8
HIRIP3
HMGXB4
HNRNPA1
HNRNPA2B1
HNRNPAB
HNRNPL
HNRNPR
HPF1
ING2
ING4
IRAK1
JADE2
JADE3
JAK1
JAK2
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM1B
KDM2A
KDM3B
KDM5A
KDM5D
KDM6A
KIF2A
KIF2C
KMT2C
KPNA1
LRIF1
LRWD1
MBD3
MCM2
MCM7
MDM2
MEN1
MGA
MIER1
MLLT1
MORF4L1
MSL3
MTA1
MTA2
MYB
NAP1L4
NASP
NBN
NCL
NCOA2
NCOA3
NOC2L
NONO
NPM1
NSD1
NSD2
ORC2
ORC3
ORC4
ORC5
PARP1
PARP2
PCGF6
PHC2
PHC3
PHF12
PHF7
PHF8
PHRF1
PIM1
POGZ
PPIB
PPM1G
PRDM2
PRKCA
PRMT5
PTBP1
PTMA
RAG1
RBBP4
RBBP5
RBBP7
RBP5
RCOR1
RING1
RIPPLY1
RNF2
RPS6KA3
RPS6KA5
RREB1
SAP30
SET
SETD2
SETD7
SETDB1
SFPQ
SGF29
SIN3A
SIN3B
SMN1
SMNDC1
SMYD3
SUPT20H
SUPT3H
SUV39H1
SUZ12
TADA1
TADA3
TAF1
TAF10
TAF11
TAF12
TAF13
TAF15
TAF1A
TAF2
TAF3
TAF4
TAF4B
TAF5
TAF5L
TAF6
TAF6L
TAF7
TAF8
TAF9
TAF9B
TBP
TCF19
TDRD3
TNPO1
TRPM7
UHRF1
WDR5
ZMYM4
ZMYND11
ZNF217
ZNF516
Entrez ID
4176
8290
HPRD ID
01154
04156
Ensembl ID
ENSG00000166508
ENSG00000168148
Uniprot IDs
A0A0S2Z4A5
C6EMX8
C9J8M6
P33993
Q16695
PDB IDs
6XTX
6XTY
7PFO
7PLO
7W1Y
7W68
8B9D
8RWV
8S09
8S0A
8S0B
8S0D
8S0E
8S0F
8W0E
8W0F
8W0G
8W0I
9CAQ
2V1D
2YBP
2YBS
3A6N
3T6R
4V2V
4V2W
6OIE
6WAT
6WAU
8VMI
8Z50
Enriched GO Terms of Interacting Partners
?
DNA Replication Initiation
DNA Replication
DNA Replication Origin Binding
DNA Metabolic Process
Nuclear Origin Of Replication Recognition Complex
Chromosome, Telomeric Region
Nucleoplasm
Regulation Of DNA Replication
Origin Recognition Complex
Double-strand Break Repair Via Break-induced Replication
Nucleus
DNA Damage Response
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
CMG Complex
MCM Complex
Regulation Of Mitotic Cell Cycle
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleic Acid Metabolic Process
Negative Regulation Of Cell Cycle
Single-stranded DNA Binding
Regulation Of Cell Cycle Process
DNA Repair
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Negative Regulation Of Cell Cycle Process
Negative Regulation Of Cell Cycle Phase Transition
Double-strand Break Repair Via Homologous Recombination
Regulation Of DNA Metabolic Process
Cellular Response To Stress
Recombinational Repair
Mitotic DNA Integrity Checkpoint Signaling
Chromosome
Nucleobase-containing Compound Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Double-strand Break Repair
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cell Cycle G1/S Phase Transition
DNA Recombination
Single-stranded DNA Helicase Activity
Regulation Of Primary Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Transcription Factor TFIIK Complex
Mitotic G2/M Transition Checkpoint
CAK-ERCC2 Complex
Mitotic DNA Replication Initiation
Regulation Of Lipid Kinase Activity
Macromolecule Metabolic Process
Chromatin Organization
Chromatin Remodeling
Nucleoplasm
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Chromatin Binding
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Histone Binding
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Chromatin
Positive Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of DNA Repair
Transcription Factor TFIID Complex
Chromosome
Protein-DNA Complex Assembly
Nucleic Acid Metabolic Process
RNA Polymerase II General Transcription Initiation Factor Activity
Transcription Factor TFTC Complex
Negative Regulation Of Gene Expression, Epigenetic
SAGA Complex
MRNA Transcription By RNA Polymerase II
Regulation Of Cellular Response To Stress
RNA Polymerase II Preinitiation Complex Assembly
Transcription Coactivator Activity
Chromosome, Telomeric Region
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?