Wiki-Pi
About
Search
People
Updates
Search
H3-4 and DNMT1
Number of citations of the paper that reports this interaction (PubMedID
30104358
)
41
Data Source:
BioGRID
(pull down)
H3-4
DNMT1
Description
H3.4 histone, cluster member
DNA methyltransferase 1
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleosome
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Chromosome
Extracellular Exosome
Heterochromatin
Female Germ Cell Nucleus
Nucleus
Nucleoplasm
Replication Fork
Pericentric Heterochromatin
Mitochondrion
Germ Cell Nucleus
Molecular Function
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
DNA Binding
Chromatin Binding
RNA Binding
DNA (cytosine-5-)-methyltransferase Activity
Protein Binding
Methyltransferase Activity
Zinc Ion Binding
Methyl-CpG Binding
DNA-methyltransferase Activity
Transferase Activity
Metal Ion Binding
LncRNA Binding
Promoter-specific Chromatin Binding
Biological Process
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Chromatin Assembly
Spermatogonial Cell Division
Regulation Of Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
DNA Methylation-dependent Constitutive Heterochromatin Formation
DNA-templated Transcription
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Methylation
Regulation Of Cell Population Proliferation
Epigenetic Programming Of Gene Expression
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
Negative Regulation Of DNA-templated Transcription
Cellular Response To Amino Acid Stimulus
Chromosomal DNA Methylation Maintenance Following DNA Replication
Cellular Response To Bisphenol A
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
Condensation of Prophase Chromosomes
DNA Damage/Telomere Stress Induced Senescence
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Meiotic recombination
Inhibition of DNA recombination at telomere
PRC2 methylates histones and DNA
NoRC negatively regulates rRNA expression
SUMOylation of DNA methylation proteins
DNA methylation
STAT3 nuclear events downstream of ALK signaling
Defective pyroptosis
Nuclear events stimulated by ALK signaling in cancer
Drugs
Procaine
Azacitidine
Procainamide
Flucytosine
Decitabine
Palifosfamide
Epigallocatechin gallate
Diseases
GWAS
Appendicular lean mass (
33097823
)
Birth weight (
31043758
)
Immature fraction of reticulocytes (
27863252
)
Narcolepsy (
24204295
)
Offspring birth weight (
31043758
)
Reticulocyte count (
27863252
)
Reticulocyte fraction of red cells (
27863252
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
195 interacting genes:
ADNP
AFF1
AHDC1
ANP32A
ASF1A
ASH2L
ATAD2
AURKA
AURKB
BACC1
BIRC5
BMI1
BPTF
BRD7
CBX1
CBX2
CBX3
CBX4
CBX5
CBX7
CBX8
CDYL
CDYL2
CHAF1A
CHAF1B
CHAMP1
CHD1
CHD4
CHD6
CHUK
COPRS
CREBBP
CTBP1
CTBP2
DCAF1
DEK
DNMT1
DOT1L
DPF2
DPY30
DYRK2
EGFR
EHMT1
EHMT2
EMSY
EP300
ERAP1
EZH2
FOXA1
GADD45A
GATAD1
GLYR1
GTF3C4
HAT1
HDAC1
HDAC2
HDAC8
HIRIP3
HMGXB4
HNRNPA1
HNRNPA2B1
HNRNPAB
HNRNPL
HNRNPR
HPF1
ING2
ING4
IRAK1
JADE2
JADE3
JAK1
JAK2
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM1B
KDM2A
KDM3B
KDM5A
KDM5D
KDM6A
KIF2A
KIF2C
KMT2C
KPNA1
LRIF1
LRWD1
MBD3
MCM2
MCM7
MDM2
MEN1
MGA
MIER1
MLLT1
MORF4L1
MSL3
MTA1
MTA2
MYB
NAP1L4
NASP
NBN
NCL
NCOA2
NCOA3
NOC2L
NONO
NPM1
NSD1
NSD2
ORC2
ORC3
ORC4
ORC5
PARP1
PARP2
PCGF6
PHC2
PHC3
PHF12
PHF7
PHF8
PHRF1
PIM1
POGZ
PPIB
PPM1G
PRDM2
PRKCA
PRMT5
PTBP1
PTMA
RAG1
RBBP4
RBBP5
RBBP7
RBP5
RCOR1
RING1
RIPPLY1
RNF2
RPS6KA3
RPS6KA5
RREB1
SAP30
SET
SETD2
SETD7
SETDB1
SFPQ
SGF29
SIN3A
SIN3B
SMN1
SMNDC1
SMYD3
SUPT20H
SUPT3H
SUV39H1
SUZ12
TADA1
TADA3
TAF1
TAF10
TAF11
TAF12
TAF13
TAF15
TAF1A
TAF2
TAF3
TAF4
TAF4B
TAF5
TAF5L
TAF6
TAF6L
TAF7
TAF8
TAF9
TAF9B
TBP
TCF19
TDRD3
TNPO1
TRPM7
UHRF1
WDR5
ZMYM4
ZMYND11
ZNF217
ZNF516
53 interacting genes:
AKT1
BAZ2A
BRAP
CBX1
CEBPA
CSNK2B
DAXX
DCAF5
DMAP1
DNMT3A
DNMT3B
DYNLL1
E2F6
EED
EEF1A1
ENSA
EZH2
FBP1
GSK3B
H2BC3
H3-4
HDAC1
HDAC2
HELLS
HMGB1
L3MBTL3
LASP1
LCOR
MCRIP1
MECP2
NGRN
NRIP1
PCLAF
PCNA
PEBP1
PHC2
PICK1
PRKAA2
RB1
RGS6
RPS6KA6
RUNX1
RUNX1T1
SETD7
SNHG6
SUMO2
SUV39H1
TRIM27
TRIM3
TSG101
UBB
UBC
YWHAQ
Entrez ID
8290
1786
HPRD ID
04156
00532
Ensembl ID
ENSG00000168148
ENSG00000130816
Uniprot IDs
Q16695
I6L9H2
P26358
Q59FP7
PDB IDs
2V1D
2YBP
2YBS
3A6N
3T6R
4V2V
4V2W
6OIE
6WAT
6WAU
8VMI
8Z50
3EPZ
3PTA
3SWR
4WXX
4YOC
4Z96
4Z97
5WVO
5YDR
6K3A
6L1F
6X9I
6X9J
6X9K
7SFC
7SFD
7SFE
7SFF
7SFG
7XI9
7XIB
8V9U
8XQC
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromatin Remodeling
Nucleoplasm
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Chromatin Binding
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Histone Binding
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Chromatin
Positive Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of DNA Repair
Transcription Factor TFIID Complex
Chromosome
Protein-DNA Complex Assembly
Nucleic Acid Metabolic Process
RNA Polymerase II General Transcription Initiation Factor Activity
Transcription Factor TFTC Complex
Negative Regulation Of Gene Expression, Epigenetic
SAGA Complex
MRNA Transcription By RNA Polymerase II
Regulation Of Cellular Response To Stress
RNA Polymerase II Preinitiation Complex Assembly
Transcription Coactivator Activity
Chromosome, Telomeric Region
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Chromatin Organization
Negative Regulation Of Metabolic Process
Chromatin Remodeling
Nucleoplasm
Heterochromatin Formation
Transcription Corepressor Activity
Chromatin Binding
Epigenetic Regulation Of Gene Expression
Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Heterochromatin
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Chromatin Silencing Complex
Cellular Response To Stress
Facultative Heterochromatin Formation
DNA Methylation-dependent Constitutive Heterochromatin Formation
Transcription Corepressor Binding
Enzyme Binding
Regulation Of Transcription By RNA Polymerase II
Constitutive Heterochromatin Formation
Rhythmic Process
DNA-binding Transcription Factor Binding
Cellular Response To Xenobiotic Stimulus
Regulation Of Proteolysis
Epigenetic Programming Of Gene Expression
DNA Binding
Macromolecule Metabolic Process
Response To Lipid
Chromosome
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
ESC/E(Z) Complex
Protein Tag Activity
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?