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H3-4 and CHD1
Number of citations of the paper that reports this interaction (PubMedID
17540172
)
0
Data Source:
HPRD
(in vitro)
H3-4
CHD1
Description
H3.4 histone, cluster member
chromodomain helicase DNA binding protein 1
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleosome
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Chromosome
Extracellular Exosome
Nuclear Chromosome
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Nucleotide Binding
DNA Binding
Chromatin Binding
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Histone Binding
Histone H3K4me3 Reader Activity
ATP-dependent Chromatin Remodeler Activity
Biological Process
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Chromatin Assembly
Spermatogonial Cell Division
Regulation Of Cell Differentiation
Chromatin Organization
Chromatin Remodeling
Nucleosome Organization
Host-mediated Activation Of Viral Transcription
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
Condensation of Prophase Chromosomes
DNA Damage/Telomere Stress Induced Senescence
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Meiotic recombination
Inhibition of DNA recombination at telomere
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Basophil percentage of white cells (
27863252
)
Eosinophil count (
27863252
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Neutrophil percentage of granulocytes (
27863252
)
Periodontitis (Mean PAL) (
24024966
)
Renal sinus fat (
22044751
)
Interacting Genes
195 interacting genes:
ADNP
AFF1
AHDC1
ANP32A
ASF1A
ASH2L
ATAD2
AURKA
AURKB
BACC1
BIRC5
BMI1
BPTF
BRD7
CBX1
CBX2
CBX3
CBX4
CBX5
CBX7
CBX8
CDYL
CDYL2
CHAF1A
CHAF1B
CHAMP1
CHD1
CHD4
CHD6
CHUK
COPRS
CREBBP
CTBP1
CTBP2
DCAF1
DEK
DNMT1
DOT1L
DPF2
DPY30
DYRK2
EGFR
EHMT1
EHMT2
EMSY
EP300
ERAP1
EZH2
FOXA1
GADD45A
GATAD1
GLYR1
GTF3C4
HAT1
HDAC1
HDAC2
HDAC8
HIRIP3
HMGXB4
HNRNPA1
HNRNPA2B1
HNRNPAB
HNRNPL
HNRNPR
HPF1
ING2
ING4
IRAK1
JADE2
JADE3
JAK1
JAK2
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM1B
KDM2A
KDM3B
KDM5A
KDM5D
KDM6A
KIF2A
KIF2C
KMT2C
KPNA1
LRIF1
LRWD1
MBD3
MCM2
MCM7
MDM2
MEN1
MGA
MIER1
MLLT1
MORF4L1
MSL3
MTA1
MTA2
MYB
NAP1L4
NASP
NBN
NCL
NCOA2
NCOA3
NOC2L
NONO
NPM1
NSD1
NSD2
ORC2
ORC3
ORC4
ORC5
PARP1
PARP2
PCGF6
PHC2
PHC3
PHF12
PHF7
PHF8
PHRF1
PIM1
POGZ
PPIB
PPM1G
PRDM2
PRKCA
PRMT5
PTBP1
PTMA
RAG1
RBBP4
RBBP5
RBBP7
RBP5
RCOR1
RING1
RIPPLY1
RNF2
RPS6KA3
RPS6KA5
RREB1
SAP30
SET
SETD2
SETD7
SETDB1
SFPQ
SGF29
SIN3A
SIN3B
SMN1
SMNDC1
SMYD3
SUPT20H
SUPT3H
SUV39H1
SUZ12
TADA1
TADA3
TAF1
TAF10
TAF11
TAF12
TAF13
TAF15
TAF1A
TAF2
TAF3
TAF4
TAF4B
TAF5
TAF5L
TAF6
TAF6L
TAF7
TAF8
TAF9
TAF9B
TBP
TCF19
TDRD3
TNPO1
TRPM7
UHRF1
WDR5
ZMYM4
ZMYND11
ZNF217
ZNF516
9 interacting genes:
BCLAF1
H3-3A
H3-4
HDAC1
NCOR1
SAFB
SPP1
SRSF3
SSRP1
Entrez ID
8290
1105
HPRD ID
04156
03668
Ensembl ID
ENSG00000168148
ENSG00000153922
Uniprot IDs
Q16695
A0A087WVF4
B3KT33
O14646
PDB IDs
2V1D
2YBP
2YBS
3A6N
3T6R
4V2V
4V2W
6OIE
6WAT
6WAU
8VMI
8Z50
2B2T
2B2U
2B2V
2B2W
2B2Y
2N39
4B4C
4NW2
4O42
5AFW
8UMG
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromatin Remodeling
Nucleoplasm
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Chromatin Binding
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Histone Binding
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Chromatin
Positive Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of DNA Repair
Transcription Factor TFIID Complex
Chromosome
Protein-DNA Complex Assembly
Nucleic Acid Metabolic Process
RNA Polymerase II General Transcription Initiation Factor Activity
Transcription Factor TFTC Complex
Negative Regulation Of Gene Expression, Epigenetic
SAGA Complex
MRNA Transcription By RNA Polymerase II
Regulation Of Cellular Response To Stress
RNA Polymerase II Preinitiation Complex Assembly
Transcription Coactivator Activity
Chromosome, Telomeric Region
Regulation Of Androgen Receptor Signaling Pathway
Chromatin Organization
Response To Macrophage Colony-stimulating Factor
Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Nucleosome Assembly
DNA Binding
Negative Regulation Of Androgen Receptor Signaling Pathway
Nucleosome Organization
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Response To Platelet-derived Growth Factor
Protein-DNA Complex Assembly
Response To Peptide
Response To Cytokine
Nucleoplasm
Nucleosomal DNA Binding
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Histone Deacetylase Complex
Embryo Implantation
Chromatin Remodeling
Heterochromatin
Constitutive Heterochromatin Formation
Adherens Junction Disassembly
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Transcription Repressor Complex
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Nucleus
Regulation Of Macromolecule Biosynthetic Process
Cell-cell Junction Disassembly
Structural Constituent Of Chromatin
Krueppel-associated Box Domain Binding
Protein-RNA Sequence-specific Adaptor Activity
Positive Regulation Of Estradiol Secretion
Regulation Of Nucleobase-containing Compound Metabolic Process
Cellular Response To Cytokine Stimulus
Kit Signaling Pathway
Protein Lysine Delactylase Activity
Fungiform Papilla Formation
Cellular Response To Leukemia Inhibitory Factor
Response To Leukemia Inhibitory Factor
Regulation Of Estradiol Secretion
Male Gonad Development
Cellular Response To Macrophage Colony-stimulating Factor Stimulus
Negative Regulation Of Mast Cell Activation Involved In Immune Response
Tyrosine Phosphorylation Of STAT Protein
Regulation Of Macromolecule Metabolic Process
Extracellular Matrix-cell Signaling
Chromatin
Gonad Development
Nucleosome
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Tagcloud (Intersection)
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