H3-4 and CHAF1B

Number of citations of the paper that reports this interaction (PubMedID 20850016)
0

Data Source:
BioGRID (unspecified method)

		H3-4	CHAF1B
Description		H3.4 histone, cluster member	chromatin assembly factor 1 subunit B
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleosome Heterochromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex
	Molecular Function	DNA Binding Protein Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding
	Biological Process	Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly Spermatogonial Cell Division Regulation Of Cell Differentiation	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex Condensation of Prophase Chromosomes DNA Damage/Telomere Stress Induced Senescence Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint Meiotic recombination Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS			Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		195 interacting genes: ADNP AFF1 AHDC1 ANP32A ASF1A ASH2L ATAD2 AURKA AURKB BACC1 BIRC5 BMI1 BPTF BRD7 CBX1 CBX2 CBX3 CBX4 CBX5 CBX7 CBX8 CDYL CDYL2 CHAF1A CHAF1B CHAMP1 CHD1 CHD4 CHD6 CHUK COPRS CREBBP CTBP1 CTBP2 DCAF1 DEK DNMT1 DOT1L DPF2 DPY30 DYRK2 EGFR EHMT1 EHMT2 EMSY EP300 ERAP1 EZH2 FOXA1 GADD45A GATAD1 GLYR1 GTF3C4 HAT1 HDAC1 HDAC2 HDAC8 HIRIP3 HMGXB4 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPL HNRNPR HPF1 ING2 ING4 IRAK1 JADE2 JADE3 JAK1 JAK2 KAT2A KAT2B KAT5 KAT6A KDM1A KDM1B KDM2A KDM3B KDM5A KDM5D KDM6A KIF2A KIF2C KMT2C KPNA1 LRIF1 LRWD1 MBD3 MCM2 MCM7 MDM2 MEN1 MGA MIER1 MLLT1 MORF4L1 MSL3 MTA1 MTA2 MYB NAP1L4 NASP NBN NCL NCOA2 NCOA3 NOC2L NONO NPM1 NSD1 NSD2 ORC2 ORC3 ORC4 ORC5 PARP1 PARP2 PCGF6 PHC2 PHC3 PHF12 PHF7 PHF8 PHRF1 PIM1 POGZ PPIB PPM1G PRDM2 PRKCA PRMT5 PTBP1 PTMA RAG1 RBBP4 RBBP5 RBBP7 RBP5 RCOR1 RING1 RIPPLY1 RNF2 RPS6KA3 RPS6KA5 RREB1 SAP30 SET SETD2 SETD7 SETDB1 SFPQ SGF29 SIN3A SIN3B SMN1 SMNDC1 SMYD3 SUPT20H SUPT3H SUV39H1 SUZ12 TADA1 TADA3 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF2 TAF3 TAF4 TAF4B TAF5 TAF5L TAF6 TAF6L TAF7 TAF8 TAF9 TAF9B TBP TCF19 TDRD3 TNPO1 TRPM7 UHRF1 WDR5 ZMYM4 ZMYND11 ZNF217 ZNF516	13 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A CUX1 H3-4 H3C6 PLEKHH1 RBBP4 SUMO2 ZNF879
Entrez ID		8290	8208
HPRD ID		04156	03147
Ensembl ID		ENSG00000168148	ENSG00000159259
Uniprot IDs		Q16695	Q13112
PDB IDs		2V1D 2YBP 2YBS 3A6N 3T6R 4V2V 4V2W 6OIE 6WAT 6WAU 8VMI 8Z50	7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Remodeling Nucleoplasm Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Chromatin Binding Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Epigenetic Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Histone Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Chromatin Positive Regulation Of Metabolic Process Regulation Of DNA Metabolic Process Regulation Of DNA Repair Transcription Factor TFIID Complex Chromosome Protein-DNA Complex Assembly Nucleic Acid Metabolic Process RNA Polymerase II General Transcription Initiation Factor Activity Transcription Factor TFTC Complex Negative Regulation Of Gene Expression, Epigenetic SAGA Complex MRNA Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress RNA Polymerase II Preinitiation Complex Assembly Transcription Coactivator Activity Chromosome, Telomeric Region	DNA Replication-dependent Chromatin Assembly Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly Cyclin-dependent Protein Kinase Activity CAF-1 Complex DNA Replication Histone Kinase Activity Protein-containing Complex Assembly Chromosome, Telomeric Region Protein-containing Complex Organization Histone Chaperone Activity Protein-containing Complex DNA Repair Cellular Component Assembly Cyclin-dependent Protein Serine/threonine Kinase Activity Cyclin Binding Response To Copper Ion Extracellular Exosome Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Prostaglandin E2 9-reductase Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity DNA Metabolic Process Pronuclear Fusion DNA Damage Response Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Histone Binding Chromatin Binding G2/M Transition Of Mitotic Cell Cycle Acetylcholine Receptor Activator Activity Regulation Of Transcription By RNA Polymerase II Lipoprotein Particle Positive Regulation Of Protein Import 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity S-nitrosoglutathione Reductase (NADPH) Activity Cell Cycle G2/M Phase Transition Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex
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