HIST3H3 and DOT1L

  • Number of citations of the paper that reports this interaction (PMID 22619169)
  • 6
  • Data Source:
  • BioGRID (enzymatic study)

HIST3H3

DOT1L

Gene Name histone cluster 3, H3 DOT1-like histone H3K79 methyltransferase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 183 interactors: ADNP AFF1 AHDC1 ANP32A ASF1A ASH2L ATAD2 AURKA AURKB BIRC5 BMI1 BPTF BRD7 C11orf30 C17orf49 CBX1 CBX2 CBX3 CBX4 CBX5 CBX7 CBX8 CCDC101 CDYL CDYL2 CHAF1A CHAF1B CHAMP1 CHD1 CHD4 CHD6 CHUK CREBBP CTBP1 CTBP2 DEK DIDO1 DOT1L DPF2 DPY30 DYRK2 EGFR EHMT1 EHMT2 EP300 ERAP1 EZH2 FOXA1 GADD45A GATAD1 GLYR1 GTF3C4 HAT1 HDAC1 HDAC2 HDAC8 HIRIP3 HMGXB4 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPK HNRNPL HNRNPR ING2 ING4 IRAK1 JADE2 JADE3 JAK1 JAK2 KAT2A KAT2B KAT5 KAT6A KDM1A KDM2A KDM3B KDM5A KDM5D KDM6A KIF2A KIF2C KMT2A KPNA1 LRIF1 LRWD1 MBD3 MCM2 MCM7 MDM2 MEN1 MGA MIER1 MLLT1 MORF4L1 MSL3 MTA1 MTA2 NAP1L4 NCL NCOA2 NCOA3 NOC2L NONO NPM1 NSD1 ORC2 ORC3 ORC4 ORC5 PCGF6 PHC2 PHC3 PHF12 PHF7 PHF8 PIM1 POGZ PPIB PPM1G PRDM2 PRKCA PRKCZ PTBP1 PTMA RAG1 RBBP4 RBBP5 RBBP7 RBP5 RCOR1 RING1 RNF2 RPS6KA3 RPS6KA5 RREB1 SAP30 SET SETD2 SETD7 SETDB1 SFPQ SIN3A SIN3B SMN1 SMNDC1 SMYD3 SUPT20H SUPT3H SUV39H1 SUZ12 TADA1 TADA3 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF2 TAF3 TAF4 TAF4B TAF5 TAF5L TAF6 TAF6L TAF7 TAF8 TAF9 TAF9B TBP TDRD3 TNPO1 TRPM7 UHRF1 VPRBP WHSC1 ZMYM4 ZNF217 ZNF516 4 interactors: HIST3H3 MLLT10 MLLT6 STAT1
Entrez ID 8290 84444
HPRD ID 04156 10455
Ensembl ID ENSG00000168148 ENSG00000104885
Uniprot IDs Q16695 Q8TEK3
PDB IDs 2V1D 2YBP 2YBS 3A6N 3T6R 1NW3 3QOW 3QOX 3SR4 3SX0 3UWP 4EK9 4EKG 4EKI 4EQZ 4ER0 4ER3 4ER5 4ER6 4ER7 4HRA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alters  annotation  ca3  candidate  cdh23  dataset  disequilibrium  ear  fdr  filtering  gwas  harbored  hypotheses  hypothetical  icsnpathway  il27ra  innate  modulates  morphogenesis  pneumoconiosis  ptprz1  rs11592462  rs2230656  rs2292151  rs8120  snps  stereocilia  strongest  ticam1 
aberrant  balanced  blasts  catalyze  considerable  depending  deregulated  disturbed  drivers  histones  indirectly  leukemia  leukemic  lysine  marks  methylated  methyltransferases  mll1  oncogenic  originating  progenitor  recurrently  repressing  residue  setd2  tightly  transformed  translocations  writers 
Tagcloud (Difference) ?
alters  annotation  ca3  candidate  cdh23  dataset  disequilibrium  ear  fdr  filtering  gwas  harbored  hypotheses  hypothetical  icsnpathway  il27ra  innate  modulates  morphogenesis  pneumoconiosis  ptprz1  rs11592462  rs2230656  rs2292151  rs8120  snps  stereocilia  strongest  ticam1 
aberrant  balanced  blasts  catalyze  considerable  depending  deregulated  disturbed  drivers  histones  indirectly  leukemia  leukemic  lysine  marks  methylated  methyltransferases  mll1  oncogenic  originating  progenitor  recurrently  repressing  residue  setd2  tightly  transformed  translocations  writers 
Tagcloud (Intersection) ?