SMAD5 and RYR2

  • Number of citations of the paper that reports this interaction (PMID 15231748)
  • 65

SMAD5

RYR2

Gene Name SMAD family member 5 ryanodine receptor 2 (cardiac)
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 19684603)
  • Exercise treadmill test traits ( 17903301)
  • Hypertension ( 17554300)
  • Obesity-related traits ( 23251661)
  • Response to cerivastatin ( 21386754)
  • Response to taxane treatment (docetaxel) ( 23006423)
Protein-Protein Interactions 44 interactors: ACVR1 ANKRD13A BCAT1 BMP6 CHMP3 COPS5 CXXC5 EP300 FLNA GDF6 HBG2 HGS HOXA13 HOXD13 MBD1 MEN1 MTMR10 NEDD4 PLEKHO1 PNKP PPIL4 PSMD11 PTPN12 RBM4 RYR2 SF3B1 SF3B3 SFPQ SMAD1 SMAD4 SMURF1 SMURF2 SNRNP70 SNRPA SOX5 SOX7 SUV39H1 SUV39H2 TOB1 U2AF2 UBA1 WWP1 ZEB2 ZNF8 14 interactors: AKAP6 ALB CACNA1C CALM1 FKBP1B HOMER1 ITPR1 MDM2 PRKACA PRKAR2A RYR1 RYR3 SMAD5 SRI
Entrez ID 4090 6262
HPRD ID 04381 01619
Ensembl ID ENSG00000113658 ENSG00000198626
Uniprot IDs Q68DB7 Q99717 Q92736
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1beta  affecting  alkaloid  anticancer  bcl  caspases  cdk1  compound  cytokines  cytotoxicity  g0  g1  inducing  k562  lamd  lamellarin  leukemia  marine  p27  panel  poorly  pronounced  smad3  stgc3  survivin  tgf  thinking  understood  way 
12kda  atlantic  bedford  biphenyls  congener  congeners  creek  dioxin  exceed  f2  fk506  fkbp12  fundulus  generations  heritable  heteroclitus  hydrocarbon  killifish  nbh  ndl  pcb  pcbs  ryanodine  ryr1  scorton  serca2  thrive  vastly 
Tagcloud (Difference) ?
1beta  affecting  alkaloid  anticancer  bcl  caspases  cdk1  compound  cytokines  cytotoxicity  g0  g1  inducing  k562  lamd  lamellarin  leukemia  marine  p27  panel  poorly  pronounced  smad3  stgc3  survivin  tgf  thinking  understood  way 
12kda  atlantic  bedford  biphenyls  congener  congeners  creek  dioxin  exceed  f2  fk506  fkbp12  fundulus  generations  heritable  heteroclitus  hydrocarbon  killifish  nbh  ndl  pcb  pcbs  ryanodine  ryr1  scorton  serca2  thrive  vastly 
Tagcloud (Intersection) ?