SMAD1 and PAK1

  • Number of citations of the paper that reports this interaction (PMID 15761153)
  • 154
  • Data Source:
  • HPRD (in vivo)

SMAD1

PAK1

Gene Name SMAD family member 1 p21 protein (Cdc42/Rac)-activated kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 138 interactors: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APP AR ARHGEF6 ARL4D BMPR1A BTBD2 BTG2 CAMSAP1 CDK7 CDK9 CHMP3 COL4A1 DVL1 ECSIT EIF2AK4 ELP3 EP300 ERBB2IP EWSR1 FBXL12 FBXO30 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC GSK3B HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ICK ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MKL2 NAT9 NEDD4 NEDD9 NEUROG1 NKX3-2 NOTCH2 OAZ1 OAZ3 PAK1 PARD3B PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STUB1 SUV39H1 TCF20 TGFBR1 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4 83 interactors: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 C5orf42 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CRIPAK CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 HGS HIST1H3A HIST1H4A HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1F PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SORBS3 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83
Entrez ID 4086 5058
HPRD ID 03356 03995
Ensembl ID ENSG00000170365 ENSG00000149269
Uniprot IDs Q15797 B3KNX7 Q13153
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Difference) ?
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Intersection) ?