SMAD1 and ACVR1

  • Number of citations of the paper that reports this interaction (PMID 9136927)
  • 74
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

SMAD1

ACVR1

Gene Name SMAD family member 1 activin A receptor, type I
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 138 interactors: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APP AR ARHGEF6 ARL4D BMPR1A BTBD2 BTG2 CAMSAP1 CDK7 CDK9 CHMP3 COL4A1 DVL1 ECSIT EIF2AK4 ELP3 EP300 ERBB2IP EWSR1 FBXL12 FBXO30 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC GSK3B HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ICK ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MKL2 NAT9 NEDD4 NEDD9 NEUROG1 NKX3-2 NOTCH2 OAZ1 OAZ3 PAK1 PARD3B PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STUB1 SUV39H1 TCF20 TGFBR1 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4 64 interactors: AP2B1 BAMBI BMP2 BMP7 BMPR1A BMPR2 CDK14 CHN1 CREBBP DCAF6 DUSP13 ENG FANCL FBXO30 FCHO1 FGD6 FKBP4 FNTA GDF5 IGSF1 IKBKB INHBA INHBB INHBC KLHL35 NEK8 NKIRAS1 NRAS NUAK2 PAK1 PLEK PLEKHB1 PLEKHJ1 RAB17 RAB25 RAB33B RAB3B RAB6B RAP2A RASD2 RASL12 RHEBL1 RHOD RHOJ RPS27A RRAS2 RXRA SMAD1 SMAD5 SMAD9 SOCS6 STX8 TGFBR1 TGFBR2 THRB TTC17 TTC27 UBA52 UBE2E3 UBXN1 USP39 VDR VEPH1 WDR61
Entrez ID 4086 90
HPRD ID 03356 00021
Ensembl ID ENSG00000170365 ENSG00000115170
Uniprot IDs Q15797 D3DPA4 Q04771
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1 3H9R 3MTF 3OOM 3Q4U 4BGG 4C02 4DYM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
advances  authors  braf  briefly  changed  counterpart  decades  divide  extremely  focus  gliomas  helped  hggs  highlight  histologic  historically  idh  lethal  ntrk  past  pdgfra  pediatric  phggs  rarity  resection  subgroups  telomeres  tools  v600e 
Tagcloud (Difference) ?
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
advances  authors  braf  briefly  changed  counterpart  decades  divide  extremely  focus  gliomas  helped  hggs  highlight  histologic  historically  idh  lethal  ntrk  past  pdgfra  pediatric  phggs  rarity  resection  subgroups  telomeres  tools  v600e 
Tagcloud (Intersection) ?