LALBA and CRYAA

Number of citations of the paper that reports this interaction (PMID 9346914)
14

Data Source:
HPRD (in vitro)

		LALBA	CRYAA
Gene Name		lactalbumin, alpha-	crystallin, alpha A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Lactose Synthase Activity Calcium Ion Binding	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding
	Biological Process	Lactose Biosynthetic Process Apoptotic Process Signal Transduction Cell-cell Signaling Defense Response To Bacterium	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Response To Stimulus Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: B4GALT1 CRYAA CRYAB HIST2H2BE HIST2H3A HSPA8 UBC	17 interactors: ALB BCL2L1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP SDCBP SPG21 WDYHV1
Entrez ID		3906	1409
HPRD ID		01024	00427
Ensembl ID		ENSG00000167531	ENSG00000160202
Uniprot IDs		P00709	E9PHE4 P02489
PDB IDs		1A4V 1B9O 1CB3 1HML 3B0I 3B0O 4L41
Enriched GO Terms of Interacting Partners?		Response To Stress Negative Regulation Of Fibril Organization Regulation Of Apoptotic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Intracellular Transport Regulation Of Cell Death Response To Stimulus Notch Signaling Pathway Regulation Of Fibril Organization Lactose Biosynthetic Process Carbohydrate Biosynthetic Process Clathrin Coat Disassembly Pathogenesis Hexose Metabolic Process Disaccharide Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Apoptotic Process MAPK Cascade Negative Regulation Of Programmed Cell Death Cellular Carbohydrate Metabolic Process Negative Regulation Of Cell Death Tubulin Complex Assembly Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Monosaccharide Metabolic Process Protein Homooligomerization Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Protein Complex Assembly Regulation Of Cellular Localization Signal Transduction By Phosphorylation Protein Folding Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Response To Hypoxia Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Acrosome Reaction Viral Protein Processing Negative Regulation Of RNA Biosynthetic Process DNA Methylation On Cytosine Development Of Secondary Sexual Characteristics Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Innate Immune Response In Mucosa Defense Response Negative Regulation Of Biosynthetic Process Oligosaccharide Biosynthetic Process Negative Regulation Of Transport Chaperone Mediated Protein Folding Requiring Cofactor Apoptotic Process Involved In Morphogenesis	Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Eye Development Lens Development In Camera-type Eye Sensory Organ Development Sensory Perception Cellular Response To Gamma Radiation Neurological System Process Bile Acid And Bile Salt Transport Response To Gamma Radiation Cellular Response To Ionizing Radiation Apoptotic Process In Bone Marrow Retina Homeostasis Maintenance Of Mitochondrion Location Lactose Biosynthetic Process Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Stimulus Interaction With Host Organ Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Suppression By Virus Of Host Apoptotic Process Anatomical Structure Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Disaccharide Metabolic Process Canalicular Bile Acid Transport Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Unfolded Protein Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Cell Death Cellular Response To Radiation System Development Response To Ionizing Radiation Protein Processing Involved In Protein Targeting To Mitochondrion Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Tubulin Complex Assembly Positive Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Stress
Tagcloud ?		casein concentration csn1s1 csn1s2 csn2 csn3 driven elf5 factorial focusing greatest incubated jak lys met methionine milk mm mtor optimum peak peaked ppm preliminary rapamycin stat stat5 supplemental upregulation	aiims beaded bfsp1 cataract congenital cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n
Tagcloud (Difference) ?		casein concentration csn1s1 csn1s2 csn2 csn3 driven elf5 factorial focusing greatest incubated jak lys met methionine milk mm mtor optimum peak peaked ppm preliminary rapamycin stat stat5 supplemental upregulation	aiims beaded bfsp1 cataract congenital cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n
Tagcloud (Intersection) ?