CRYAA and CRYZ

Number of citations of the paper that reports this interaction (PMID 11672428)
7

Data Source:
HPRD (in vitro)

		CRYAA	CRYZ
Gene Name		crystallin, alpha A	crystallin, zeta (quinone reductase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	MRNA 3'-UTR Binding NADPH:quinone Reductase Activity Zinc Ion Binding NADPH Binding NADH Binding
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Response To Stimulus Protein Homooligomerization	Visual Perception Xenobiotic Catabolic Process Protein Homotetramerization Oxidation-reduction Process
Pathways
Drugs			Dicumarol 2\'-Monophosphoadenosine 5\'-Diphosphoribose
Diseases
GWAS			Resistin levels ( 22843503)
Protein-Protein Interactions		17 interactors: ALB BCL2L1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP SDCBP SPG21 WDYHV1	1 interactors: CRYAA
Entrez ID		1409	1429
HPRD ID		00427	00437
Ensembl ID		ENSG00000160202	ENSG00000116791
Uniprot IDs		E9PHE4 P02489	Q08257
PDB IDs			1YB5
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Eye Development Lens Development In Camera-type Eye Sensory Organ Development Sensory Perception Cellular Response To Gamma Radiation Neurological System Process Bile Acid And Bile Salt Transport Response To Gamma Radiation Cellular Response To Ionizing Radiation Apoptotic Process In Bone Marrow Retina Homeostasis Maintenance Of Mitochondrion Location Lactose Biosynthetic Process Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Stimulus Interaction With Host Organ Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Suppression By Virus Of Host Apoptotic Process Anatomical Structure Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Disaccharide Metabolic Process Canalicular Bile Acid Transport Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Unfolded Protein Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Cell Death Cellular Response To Radiation System Development Response To Ionizing Radiation Protein Processing Involved In Protein Targeting To Mitochondrion Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Tubulin Complex Assembly Positive Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Stress
Tagcloud ?		aiims beaded bfsp1 cataract congenital cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	1mio alphaa auges betab2 cryaa cryab cryb cryba1 cryba2 cryba4 crybb1 crybb3 cryg cryga cryge crygf crygn crygs crym crystallins duplets greek lichtbrechenden medien morner opacification proteinsubstanzen symbols untersuchungen
Tagcloud (Difference) ?		aiims beaded bfsp1 cataract congenital crybb2 crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	1mio alphaa auges betab2 cryb cryba2 cryg cryga cryge crygf crygn crym crystallins duplets greek lichtbrechenden medien morner opacification proteinsubstanzen symbols untersuchungen
Tagcloud (Intersection) ?		cryaa cryab cryba1 cryba4 crybb1 crybb3 crygs