CRYAA and RNGTT

Number of citations of the paper that reports this interaction (PubMedID 24453475)
30

Data Source:
BioGRID (pull down)

		CRYAA	RNGTT
Description		crystallin alpha A	RNA guanylyltransferase and 5'-phosphatase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Nucleus Nucleoplasm
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	Nucleotide Binding Catalytic Activity MRNA Guanylyltransferase Activity Polynucleotide 5'-phosphatase Activity Phosphoprotein Phosphatase Activity Protein Binding ATP Binding GTP Binding RNA Guanylyltransferase Activity Transferase Activity Nucleotidyltransferase Activity Hydrolase Activity Inorganic Triphosphate Phosphatase Activity MRNA 5'-triphosphate Monophosphatase Activity
	Biological Process	Response To Hypoxia Lens Development In Camera-type Eye Lens Morphogenesis In Camera-type Eye Apoptotic Process Mitochondrion Organization Actin Filament Organization Microtubule-based Process Tubulin Complex Assembly Visual Perception Response To Heat Negative Regulation Of Gene Expression Positive Regulation Of Cell Growth Negative Regulation Of Intracellular Transport Protein Refolding Response To Hydrogen Peroxide Camera-type Eye Development Negative Regulation Of Apoptotic Process Embryonic Camera-type Eye Morphogenesis Protein Stabilization Apoptotic Process Involved In Morphogenesis Response To UV-A Lens Fiber Cell Morphogenesis	Nucleobase-containing Compound Metabolic Process 7-methylguanosine MRNA Capping RNA Processing MRNA Processing
Pathways			RNA Pol II CTD phosphorylation and interaction with CE during HIV infection mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Age-related nuclear cataracts ( 24951543 33311586) Diastolic blood pressure ( 27618452 27841878 28135244 28739976) Metabolite levels ( 23823483) Systolic blood pressure ( 27618452 27841878 28739976)	Colorectal or endometrial cancer ( 26621817) Depression in smokers ( 30219690) Graft survival time in renal transplantation (donor effect) ( 32080893) Height ( 31562340) Response to statin therapy ( 20339536) Simvastatin-induced myopathy ( 31220337) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		134 interacting genes: - ADPRHL1 AKT3 ALB ALDH1L2 ANKRD44 APPL2 ARFGAP1 ARMCX4 ARRDC1-AS1 ATG16L1 BCL2L1 BORA BTRC CAMKK2 CD209 CDC40 CEBPZ CENPH CER1 CNOT8 COPB2 CRTAC1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS CSTF2T DCAF11 DCAF8 DCK DDX3X DUS4L E2F7 EEPD1 ETFB EYA4 FAM131B FAM131C FAM182A FASN GIGYF2 GLYATL1 GNAI2 GORASP2 GSTZ1 HABP4 HCLS1 HSPB1 HSPB2 IGHG1 IGKV1-5 JKAMP KBTBD12 KIZ KNG1 LALBA LARP6 LIMA1 MAP3K7CL MAPKBP1 MCM7 MCRS1 MINDY1 MIP MPHOSPH6 MTERF4 MYO5C NAT9 NCF4 NTAQ1 NUP43 OSBPL3 OTOGL OTULIN PABIR2 PAFAH1B1 PCYT2 PHC1 PLAUR PMS2 PRM2 PSMB6 PTPN2 PTTG2 QRICH1 RAB24 RAB29 RAB3C RAB40B RAB43 RAD51 RBBP7 RNASEH1 RNGTT RPS6KA5 SDCBP SEC24C SEH1L SESN2 SGCD SLC20A1 SLC25A25 SLC25A26 SLC25A28 SPG21 SSBP4 SULF1 SYK TASL TEAD4 TFDP1 TGOLN2 TLE4 TMEM254 TMEM52B TSR3 TTC27 TTC39B TUBAL3 TUBGCP5 UBR2 UPP1 WDR55 WDR83 WIPI2 WWC2 ZIM2 ZNF3 ZNF639 ZSCAN20	4 interacting genes: APPBP2 CEBPA CRYAA RNMT
Entrez ID		1409	8732
HPRD ID		00427	04621
Ensembl ID		ENSG00000160202	ENSG00000111880
Uniprot IDs		A0A8C8KJZ9 P02489	B4DSJ8 O60942
PDB IDs		6T1R	2C46 3S24 8P4A 8P4B 8P4C 8P4D 8P4E 8W8E 8W8F
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye	Granulocyte Differentiation Mitochondrion Organization Lung Development RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission MRNA Capping Enzyme Complex MRNA 5'-cap (guanine-N7-)-methyltransferase Activity MRNA Cap Methyltransferase RNMT:RAMAC Complex RNA 5'-cap (guanine-N7)-methylation Myeloid Leukocyte Differentiation CHOP-C/EBP Complex Response To Phenylpropanoid White Fat Cell Proliferation Myeloid Cell Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Lens Fiber Cell Morphogenesis Cell Morphogenesis Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Regulation Of NK T Cell Differentiation 7-methylguanosine MRNA Capping RNA (guanine-N7)-methylation Fat Cell Proliferation Microvesicle Leukocyte Differentiation Response To Lithium Ion Transcription By RNA Polymerase I Urea Metabolic Process Regulation Of Hematopoietic Stem Cell Proliferation Cellular Response To Lithium Ion HMG Box Domain Binding RNA Metabolic Process Nitrogen Cycle Metabolic Process White Fat Cell Differentiation Urea Cycle Interleukin-6-mediated Signaling Pathway Animal Organ Development Positive Regulation Of Cell Activation STAT Family Protein Binding Osteoblast Development Tubulin Complex Assembly Response To UV-A Embryonic Camera-type Eye Morphogenesis Lens Morphogenesis In Camera-type Eye Anterograde Synaptic Vesicle Transport AP-3 Adaptor Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?