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CRYAA and LARP6
Number of citations of the paper that reports this interaction (PubMedID
24453475
)
30
Data Source:
BioGRID
(pull down)
CRYAA
LARP6
Description
crystallin alpha A
La ribonucleoprotein 6, translational regulator
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Protein-containing Complex
Nucleus
Cytoplasm
Ribonucleoprotein Complex
Molecular Function
Structural Molecule Activity
Structural Constituent Of Eye Lens
Protein Binding
Identical Protein Binding
Metal Ion Binding
Unfolded Protein Binding
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Myosin Binding
RNA Stem-loop Binding
MRNA 5'-UTR Binding
Sequence-specific MRNA Binding
Biological Process
Response To Hypoxia
Lens Development In Camera-type Eye
Lens Morphogenesis In Camera-type Eye
Apoptotic Process
Mitochondrion Organization
Actin Filament Organization
Microtubule-based Process
Tubulin Complex Assembly
Visual Perception
Response To Heat
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Growth
Negative Regulation Of Intracellular Transport
Protein Refolding
Response To Hydrogen Peroxide
Camera-type Eye Development
Negative Regulation Of Apoptotic Process
Embryonic Camera-type Eye Morphogenesis
Protein Stabilization
Apoptotic Process Involved In Morphogenesis
Response To UV-A
Lens Fiber Cell Morphogenesis
RNA Processing
Regulation Of Translation
Positive Regulation Of Collagen Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Age-related nuclear cataracts (
24951543
33311586
)
Diastolic blood pressure (
27618452
27841878
28135244
28739976
)
Metabolite levels (
23823483
)
Systolic blood pressure (
27618452
27841878
28739976
)
Insulin-related traits (multivariate analysis) (
32002517
)
Proinsulin levels (
21873549
)
Interacting Genes
134 interacting genes:
-
ADPRHL1
AKT3
ALB
ALDH1L2
ANKRD44
APPL2
ARFGAP1
ARMCX4
ARRDC1-AS1
ATG16L1
BCL2L1
BORA
BTRC
CAMKK2
CD209
CDC40
CEBPZ
CENPH
CER1
CNOT8
COPB2
CRTAC1
CRYAB
CRYBA1
CRYBB2
CRYGC
CRYGD
CRYZ
CS
CSTF2T
DCAF11
DCAF8
DCK
DDX3X
DUS4L
E2F7
EEPD1
ETFB
EYA4
FAM131B
FAM131C
FAM182A
FASN
GIGYF2
GLYATL1
GNAI2
GORASP2
GSTZ1
HABP4
HCLS1
HSPB1
HSPB2
IGHG1
IGKV1-5
JKAMP
KBTBD12
KIZ
KNG1
LALBA
LARP6
LIMA1
MAP3K7CL
MAPKBP1
MCM7
MCRS1
MINDY1
MIP
MPHOSPH6
MTERF4
MYO5C
NAT9
NCF4
NTAQ1
NUP43
OSBPL3
OTOGL
OTULIN
PABIR2
PAFAH1B1
PCYT2
PHC1
PLAUR
PMS2
PRM2
PSMB6
PTPN2
PTTG2
QRICH1
RAB24
RAB29
RAB3C
RAB40B
RAB43
RAD51
RBBP7
RNASEH1
RNGTT
RPS6KA5
SDCBP
SEC24C
SEH1L
SESN2
SGCD
SLC20A1
SLC25A25
SLC25A26
SLC25A28
SPG21
SSBP4
SULF1
SYK
TASL
TEAD4
TFDP1
TGOLN2
TLE4
TMEM254
TMEM52B
TSR3
TTC27
TTC39B
TUBAL3
TUBGCP5
UBR2
UPP1
WDR55
WDR83
WIPI2
WWC2
ZIM2
ZNF3
ZNF639
ZSCAN20
5 interacting genes:
ADARB1
APP
CRYAA
MIR141
MIR145
Entrez ID
1409
55323
HPRD ID
00427
10966
Ensembl ID
ENSG00000160202
ENSG00000166173
Uniprot IDs
A0A8C8KJZ9
P02489
Q9BRS8
PDB IDs
6T1R
2MTF
2MTG
Enriched GO Terms of Interacting Partners
?
Structural Constituent Of Eye Lens
Lens Development In Camera-type Eye
Hypoglossal Nerve Morphogenesis
Negative Regulation Of Metabolic Process
Muscle Tissue Morphogenesis
Negative Regulation Of Macromolecule Metabolic Process
Anatomical Structure Morphogenesis
Regulation Of Protein Metabolic Process
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Translation
Negative Regulation Of Gene Expression
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Regulation Of Inflammatory Response
MiRNA-mediated Gene Silencing By Inhibition Of Translation
RISC Complex
MRNA Base-pairing Post-transcriptional Repressor Activity
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Interleukin-16 Production
Negative Regulation Of Cell Population Proliferation
Regulation Of Cell Population Proliferation
Axonogenesis
Spinal Cord Ventral Commissure Morphogenesis
Facial Nerve Morphogenesis
Negative Regulation Of Protein Metabolic Process
Acetylcholine Receptor Activator Activity
PTB Domain Binding
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Endosome To Plasma Membrane Transport Vesicle
Post-transcriptional Regulation Of Gene Expression
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Lipoprotein Particle
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
MRNA 3'-UTR Binding
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Negative Regulation Of Transformation Of Host Cell By Virus
Post-transcriptional Gene Silencing
MiRNA-mediated Post-transcriptional Gene Silencing
Regulation Of Transformation Of Host Cell By Virus
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Apoptotic Process
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Double-stranded RNA Adenosine Deaminase Activity
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