IFT20 and CLEC4M

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFT20	CLEC4M
Description		intraflagellar transport 20	C-type lectin domain family 4 member M
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Membrane Host Cell
	Molecular Function	Opsin Binding Protein Binding Small GTPase Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Pattern Recognition Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Adaptive Immune Response Immune System Process Endocytosis Immune Response Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Symbiont Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Peptide Antigen Transport Intracellular Transport Of Virus
Pathways		Intraflagellar transport Intraflagellar transport	RSV-host interactions
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Lipoprotein (a) levels ( 33730874) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) vWF levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	6 interacting genes: CD209 ICAM3 IFT20 ITGAM PLPP6 SNCA
Entrez ID		90410	10332
HPRD ID		17137	12060
Ensembl ID		ENSG00000109083	ENSG00000104938
Uniprot IDs		A0A087X2B4 Q8IY31	A0A7P0MMK7 Q9H2X3
PDB IDs			1K9J 1SL6 1XAR 1XPH 3JQH 8RCY
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection	Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Catecholamine Metabolic Process Endocytosis Import Into Cell Regulation Of Dopamine Metabolic Process Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Vesicle-mediated Transport Positive Regulation Of Reactive Oxygen Species Metabolic Process Macrophage Activation Positive Regulation Of Exocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission B Cell Adhesion Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Cell-cell Adhesion Response To External Biotic Stimulus Integrin AlphaM-beta2 Complex Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Opsin Transport Intraciliary Transport Particle Regulation Of Reactive Oxygen Species Metabolic Process Innate Immune Response Positive Regulation Of Neutrophil Degranulation Response To Curcumin Vertebrate Eye-specific Patterning Myeloid Leukocyte Activation Regulation Of Immune System Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Regulation Of Cell Activation Negative Regulation Of Chaperone-mediated Autophagy Peptide Antigen Transport Kinociliary Basal Body Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Integrin Binding Positive Regulation Of Microglial Cell Mediated Cytotoxicity Complement-mediated Synapse Pruning Regulation Of Serotonin Uptake Opsin Binding Receptor-mediated Endocytosis
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