IFT20 and KIF3B

Number of citations of the paper that reports this interaction (PubMedID 12821668)
0

Data Source:
HPRD (in vivo)

		IFT20	KIF3B
Description		intraflagellar transport 20	kinesin family member 3B
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body	Cytoplasm Centrosome Cytosol Cytoskeleton Kinesin Complex Plus-end Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Membrane Kinesin II Complex Axon Dendrite Midbody Dendrite Cytoplasm Cell Projection Dendritic Spine Synapse Extracellular Exosome Ciliary Tip Postsynapse Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	Opsin Binding Protein Binding Small GTPase Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Small GTPase Binding Intraciliary Transport Particle B Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Axo-dendritic Transport Anterograde Axonal Transport Vesicle-mediated Transport Protein-containing Complex Localization Positive Regulation Of Cytokinesis Opsin Transport Intraciliary Transport Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
Pathways		Intraflagellar transport Intraflagellar transport	Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Age at first sexual intercourse ( 27089180 34211149) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Monocyte count ( 32888494) Monocyte percentage of white cells ( 27863252)
Interacting Genes		46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	12 interacting genes: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L PRC1 RAB4A SASH1
Entrez ID		90410	9371
HPRD ID		17137	04781
Ensembl ID		ENSG00000109083	ENSG00000101350
Uniprot IDs		A0A087X2B4 Q8IY31	O15066
PDB IDs			3B6U
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection	Positive Regulation Of JUN Kinase Activity Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Kinase Activity Positive Regulation Of MAP Kinase Activity Kinesin II Complex Spindle Microtubule Ciliary Tip Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Positive Regulation Of Protein Serine/threonine Kinase Activity Plus-end-directed Vesicle Transport Along Microtubule Plus-end-directed Organelle Transport Along Microtubule Plasma Membrane Bounded Cell Projection Organization Microtubule-based Transport Regulation Of MAP Kinase Activity JUN Kinase Kinase Kinase Activity Axo-dendritic Transport Positive Regulation Of Phosphorylation Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of JNK Cascade Cell Projection Organization Positive Regulation Of Catalytic Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Microtubule-based Movement MAP Kinase Kinase Kinase Activity Regulation Of JNK Cascade Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation BHLH Transcription Factor Binding Positive Regulation Of MAPK Cascade Neuron Projection Development Kinesin Binding Photoreceptor Connecting Cilium Regulation Of Catalytic Activity Vesicle Transport Along Microtubule Kinesin Complex Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Receptor Localization To Synapse Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning Microtubule Cytoskeleton
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