IFT20 and CD209

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFT20	CD209
Description		intraflagellar transport 20	CD209 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Host Cell
	Molecular Function	Opsin Binding Protein Binding Small GTPase Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Adaptive Immune Response Immune System Process Endocytosis Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Symbiont Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion Positive Regulation Of Viral Life Cycle
Pathways		Intraflagellar transport Intraflagellar transport	CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions RSV-host interactions
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Blood protein levels ( 30072576)
Interacting Genes		46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	10 interacting genes: CEACAM1 CLEC4M CLU CRYAA ICAM2 ICAM3 IFT20 ITGAM TCEAL8 VAC14
Entrez ID		90410	30835
HPRD ID		17137	05241
Ensembl ID		ENSG00000109083	ENSG00000090659
Uniprot IDs		A0A087X2B4 Q8IY31	B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12
PDB IDs			1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV 7NL6 7NL7 9EMQ 9EMR 9EMS
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection	Cell-cell Adhesion Endocytosis Cell Adhesion Amyloid-beta Clearance Integrin Binding Receptor-mediated Endocytosis Microglial Cell Activation Regulation Of Vesicle-mediated Transport Leukocyte Activation Involved In Inflammatory Response Import Into Cell Signaling Receptor Activity Macrophage Activation Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction PAS Complex Tertiary Granule Membrane Microvillus Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Negative Regulation Of Hepatocyte Proliferation Regulation Of Transport Regulation Of Leukocyte Mediated Cytotoxicity Specific Granule Membrane Integrin-mediated Signaling Pathway Cell Periphery Amyloid-beta Binding Negative Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of Neurofibrillary Tangle Assembly Central Nervous System Myelin Maintenance Immune Complex Clearance Integrin AlphaM-beta2 Complex Positive Regulation Of Neutrophil Degranulation Response To Curcumin Vertebrate Eye-specific Patterning ICAM-3 Receptor Activity Peptide Antigen Transport Kinociliary Basal Body Opsin Transport Intraciliary Transport Particle Unfolded Protein Binding Insulin Catabolic Process Regulation Of Regulated Secretory Pathway Regulation Of Receptor-mediated Endocytosis Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Chromaffin Granule Negative Regulation Of Dopamine Metabolic Process Positive Regulation Of Microglial Cell Mediated Cytotoxicity Complement-mediated Synapse Pruning Opsin Binding
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