IFT20 and PPP1R11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFT20	PPP1R11
Description		intraflagellar transport 20	protein phosphatase 1 regulatory inhibitor subunit 11
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body	Nucleus Cytoplasm
	Molecular Function	Opsin Binding Protein Binding Small GTPase Binding	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Transferase Activity Phosphatase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Defense Response To Gram-positive Bacterium
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Lipid metabolism phenotypes ( 22286219)
Interacting Genes		46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	10 interacting genes: AKT1 IFT20 LATS1 PPP1CA PPP1CB PPP1CC PPP1R3A UBXN2B VCP YAF2
Entrez ID		90410	6992
HPRD ID		17137	09449
Ensembl ID		ENSG00000109083	ENSG00000204619
Uniprot IDs		A0A087X2B4 Q8IY31	A2BEK1 O60927
PDB IDs			8DWK 8DWL 8U5G
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection	Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process PTW/PP1 Phosphatase Complex Regulation Of Generation Of Precursor Metabolites And Energy Carbohydrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Response To Radiation Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Generation Of Precursor Metabolites And Energy Regulation Of Glycogen Biosynthetic Process Response To Light Stimulus Circadian Rhythm Regulation Of Glycogen Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Protein Localization Positive Regulation Of Cellular Component Biogenesis Circadian Regulation Of Gene Expression Postsynapse Regulation Of Organelle Assembly Glutamatergic Synapse Regulation Of Canonical Wnt Signaling Pathway Rhythmic Process Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Positive Regulation Of Cellular Component Organization Positive Regulation Of Organelle Assembly Regulation Of Synapse Organization Protein Phosphatase Type 1 Complex Regulation Of Translational Initiation Regulation Of Wnt Signaling Pathway Regulation Of Small Molecule Metabolic Process Regulation Of Circadian Rhythm Positive Regulation Of Glycogen Biosynthetic Process Mammary Gland Epithelial Cell Differentiation Positive Regulation Of Protein Localization To Cell Surface Regulation Of Proteolysis Dephosphorylation Phosphate-containing Compound Metabolic Process Phosphoprotein Phosphatase Activity Regulation Of Oxidative Phosphorylation Positive Regulation Of Glial Cell Proliferation Intracellular Signaling Cassette Negative Regulation Of Lipid Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?