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ANXA1 and COPS6
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
ANXA1
COPS6
Description
annexin A1
COP9 signalosome subunit 6
Image
GO Annotations
Cellular Component
Cornified Envelope
Phagocytic Cup
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Actin Filament
Plasma Membrane
Adherens Junction
Focal Adhesion
Cilium
Cell Surface
Endosome Membrane
Vesicle Membrane
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Cytoplasmic Vesicle Membrane
Extracellular Matrix
Cytoplasmic Vesicle
Motile Cilium
Early Endosome Membrane
Vesicle
Sarcolemma
Cell Projection
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Molecular Function
Phosphatidylserine Binding
Phospholipase Inhibitor Activity
Signaling Receptor Binding
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipid Binding
Lipid Binding
Phospholipase A2 Inhibitor Activity
Metal Ion Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
Protein Binding
Peptidase Activity
Metal-dependent Deubiquitinase Activity
Biological Process
Neutrophil Homeostasis
Adaptive Immune Response
Immune System Process
Monocyte Chemotaxis
Regulation Of Leukocyte Migration
Phagocytosis
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Cell Shape
Myoblast Migration Involved In Skeletal Muscle Regeneration
Peptide Cross-linking
Actin Cytoskeleton Organization
Keratinocyte Differentiation
Positive Regulation Of Vesicle Fusion
Regulation Of Interleukin-1 Production
Negative Regulation Of Interleukin-8 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Neutrophil Apoptotic Process
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of T Cell Proliferation
Neutrophil Activation
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Innate Immune Response
Positive Regulation Of T-helper 1 Cell Differentiation
Negative Regulation Of T-helper 2 Cell Differentiation
Negative Regulation Of Exocytosis
Alpha-beta T Cell Differentiation
Regulation Of Hormone Secretion
Arachidonate Secretion
Regulation Of Inflammatory Response
Negative Regulation Of Transport
Positive Regulation Of Multicellular Organismal Process
Cellular Response To Glucocorticoid Stimulus
Granulocyte Chemotaxis
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Wound Healing
Neutrophil Clearance
Cell-cell Adhesion
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein Deneddylation
Protein Neddylation
Regulation Of Protein Neddylation
Pathways
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
Smooth Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Developmental Lineage of Pancreatic Ductal Cells
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation
Drugs
Amcinonide
Fluocinolone acetonide
Hydrocortisone
Methylprednisolone
Clobetasol propionate
Budesonide
Dexamethasone
Cortisone acetate
Hydrocortisone aceponate
Hydrocortisone acetate
Hydrocortisone butyrate
Hydrocortisone cypionate
Hydrocortisone phosphate
Hydrocortisone probutate
Hydrocortisone valerate
Prednisolone phosphate
Dexamethasone acetate
Betamethasone phosphate
Diseases
GWAS
Chronotype (
30696823
)
Cortical surface area (
32963231
)
Cortical volume (
32963231
)
Metabolite levels (
23823483
)
Parkinson's disease (
26227905
)
Schizophrenia, bipolar disorder and depression (combined) (
20713499
)
Urate levels in obese individuals (
25811787
)
Brain morphology (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
80 interacting genes:
AP2A2
APBB1
BUB3
CCN1
CCT7
CD274
CD44
CDC5L
CDH13
CLIC1
CLTC
COPS6
CORO1C
CSAD
CZIB
DAPK3
DDB1
DDX3X
DYSF
EEF2
EGFR
EIF2S1
EPHA2
ERG28
FAF1
FGFBP1
FLOT1
FLOT2
FPR1
G3BP2
GAPDH
GAPDHS
GNL3
HMGA1
HSP90AB1
HSPB1
IFIT1
IFIT3
IGF2BP1
IGF2BP3
KLHL23
KMT2B
KRT8
LGALS3
LGALS8
LMNA
LMO7
LNPK
LRIF1
MEIS2
MEN1
MYBBP1A
MYH10
MYH9
NOP58
OTUB1
PARP1
PARP9
PHB2
PRKCI
RCC2
S100A11
SRC
STRAP
SUMO2
TCP1
TGM2
TOE1
TRAF4
TRPM7
UBE2D1
UBE2I
UBE3A
UCHL5
UGDH
UNC119
USP7
XRCC1
XRCC6
YWHAQ
95 interacting genes:
ANXA1
ANXA7
ASH2L
BFSP2
BTBD2
C1orf174
C4orf17
CASP3
CASP6
CASP7
CASP8
CCBE1
CCDC106
CDH10
CDKN1A
CDKN2C
CHRNB1
COPS2
COPS3
COPS4
COPS5
COPS8
COX17
COX5A
CRELD1
CRIPTO
CUL1
CUL5
DIS3L2
DLEU1
DSP
EDN1
EIF3E
EMD
EP300
ERH
FAU
GPS1
HMOX2
LAMA4
LPL
MAP3K1
MAP7D1
MAPK1
MAPK6
MAPKAPK3
MIF
MNAT1
MYCBP
NEDD8
NR3C1
ORAI2
PAEP
PAFAH1B3
PBX2
PDZK1IP1
PFKL
PHYHIP
PMF1
PRKRA
PSAP
PSMD11
PTEN
QTRT1
RAB27A
RBX1
RFC5
ROGDI
RPA2
RPL15
S100A10
SAT1
SERPINA5
SERPINB9
SHANK3
SHC3
SLC2A1
SMN1
SNRPG
STAMBPL1
STK40
STX5
SULT1E1
TK1
TP53
TP63
TRDMT1
TRIB3
UBC
USHBP1
VIM
WIPI2
ZEB2
ZFHX3
ZNF24
Entrez ID
301
10980
HPRD ID
01060
16735
Ensembl ID
ENSG00000135046
ENSG00000168090
Uniprot IDs
P04083
Q5TZZ9
Q7L5N1
PDB IDs
1AIN
1BO9
1QLS
5VFW
4D10
4D18
4QFT
4R14
4WSN
6R6H
6R7F
6R7H
6R7I
8H38
8H3A
8H3F
Enriched GO Terms of Interacting Partners
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Regulation Of Primary Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Macromolecule Metabolic Process
Focal Adhesion
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Telomere Maintenance
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Cytosol
Nucleus
RNA Binding
Positive Regulation Of Protein Localization
Negative Regulation Of Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Cytoplasm
Extracellular Exosome
MRNA 5'-UTR Binding
Positive Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Chromosome Organization
Regulation Of Protein Modification Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Apoptotic Process
Regulation Of DNA Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Protein Localization
Regulation Of Cell Adhesion
Perinuclear Region Of Cytoplasm
Biological Process Involved In Interaction With Host
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Negative Regulation Of Macromolecule Biosynthetic Process
Signal Transduction
Cellular Response To Stress
Negative Regulation Of Biosynthetic Process
Regulation Of Signal Transduction
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Lamellipodium
Negative Regulation Of Protein Metabolic Process
Regulation Of Signaling
Intracellular Signal Transduction
Response To Stress
Regulation Of Gene Expression
Disordered Domain Specific Binding
Flotillin Complex
Protein Binding
Protein Neddylation
Protein Deneddylation
Regulation Of Protein Neddylation
Nucleoplasm
Heart Development
COP9 Signalosome
Developmental Process
Cytosol
Cellular Response To Staurosporine
Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Metabolic Process
Ubiquitin Protein Ligase Binding
Signal Transduction By P53 Class Mediator
Cellular Response To Nutrient Levels
Protein Binding
Positive Regulation Of Neuron Apoptotic Process
Protease Binding
Pyroptotic Inflammatory Response
Protein Modification By Small Protein Removal
Nucleus
Animal Organ Development
Regulation Of Cell Cycle G1/S Phase Transition
Cytoplasm
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Developmental Process
Cell Differentiation
Macromolecule Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Keratinocyte Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of Macromolecule Metabolic Process
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Scaffold Protein Binding
MAPK Cascade
Cellular Response To Alkaloid
Regulation Of Protein Modification Process
Positive Regulation Of Programmed Cell Death
Post-translational Protein Modification
Protein Modification Process
Regulation Of Post-translational Protein Modification
Protein Tag Activity
Cullin-RING Ubiquitin Ligase Complex
Protein-containing Complex
Cellular Response To Starvation
Response To Nutrient Levels
Mitotic G1 DNA Damage Checkpoint Signaling
Rhythmic Synaptic Transmission
G1/S Transition Of Mitotic Cell Cycle
Mitotic G1/S Transition Checkpoint Signaling
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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