MLH3 and ZDHHC17

Number of citations of the paper that reports this interaction (PMID 24705354)
0

Data Source:
BioGRID (two hybrid)

		MLH3	ZDHHC17
Gene Name		mutL homolog 3	zinc finger, DHHC-type containing 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptonemal Complex Male Germ Cell Nucleus Nucleus Chiasma Mismatch Repair Complex	Golgi Membrane Cytoplasm Golgi Apparatus Integral Component Of Membrane Golgi-associated Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Satellite DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding ATPase Activity Centromeric DNA Binding Mismatched DNA Binding	Signal Transducer Activity Protein Binding Zinc Ion Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding
	Biological Process	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis Female Meiosis I Protein Localization	Signal Transduction Magnesium Ion Transport Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Meiotic recombination
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		4 interactors: AR MLH1 MSH4 ZDHHC17	191 interactors: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM122C FAM135B FAM207A FAM9A FBXO18 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 HBG1 HECTD3 HIST1H2BH HIST1H3H HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT HYPM IFT20 IFT57 INPP5D JMJD7-PLA2G4B KIAA0141 KIAA0226L KIAA0408 KIAA0907 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LOC401296 LOC554206 LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF OBFC1 ODF2 OFCC1 OTUD7B OTX2 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY4 SREBF2 SRSF4 STK25 SUMF2 SYT1 TAF8 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZCCHC6 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		27030	23390
HPRD ID		05094	09697
Ensembl ID		ENSG00000119684	ENSG00000186908
Uniprot IDs		Q2M1Z1 Q9UHC1	Q8IUH5
PDB IDs			3EU9
Enriched GO Terms of Interacting Partners?		Reciprocal Meiotic Recombination Synapsis Homologous Chromosome Segregation Meiotic Chromosome Segregation Developmental Process Involved In Reproduction Meiosis I Female Gamete Generation Negative Regulation Of Integrin Biosynthetic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Meiotic Nuclear Division Negative Regulation Of Mitotic Recombination Meiotic Cell Cycle Positive Regulation Of Integrin Biosynthetic Process Single Organism Reproductive Process Chromosome Segregation DNA Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Regulation Of Integrin Biosynthetic Process Reproductive Process Sex Differentiation Chiasma Assembly Spindle Midzone Assembly Positive Regulation Of Transcription From RNA Polymerase III Promoter Resolution Of Meiotic Recombination Intermediates Cellular Component Assembly Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Reproductive Structure Development Reproductive System Development Spermatogenesis Male Gamete Generation Lipoprotein Transport Magnesium Ion Transport Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Regulation Of Transcription From RNA Polymerase III Promoter Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Gamete Generation Protein Palmitoylation Metaphase Plate Congression Somatic Recombination Of Immunoglobulin Gene Segments Androgen Receptor Signaling Pathway Somatic Diversification Of Immunoglobulins Sexual Reproduction Multicellular Organismal Reproductive Process Regulation Of Establishment Of Protein Localization To Plasma Membrane	Regulation Of Metabolic Process Transcription, DNA-templated RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Cellular Process Organelle Organization Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Neurotransmitter Uptake Developmental Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Golgi Organization Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Transcription, DNA-templated Chromatin Organization Cellular Component Assembly Regulation Of Gene Silencing Gene Silencing RNA 3'-end Processing Embryo Development Visual Learning Regulation Of Cell Projection Organization Visual Behavior RNA Processing
Tagcloud ?		aggregated anaplastic atc braf cdkn1b cdkn2c ctnnb1 eif1ax exclusive exome harbored hypermutator landscape mismatch mlh1 msh5 msh6 mutational mutually nf1 nf2 nras ontology pik3ca ret unresponsive ush2a v600e	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 il6st jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Difference) ?		aggregated anaplastic atc braf cdkn1b cdkn2c ctnnb1 eif1ax exclusive exome harbored hypermutator landscape mismatch mlh1 msh5 msh6 mutational mutually nf1 nf2 nras ontology pik3ca ret unresponsive ush2a v600e	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 il6st jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Intersection) ?