GHR and SOCS1

  • Number of citations of the paper that reports this interaction (PMID 10585430)
  • 43
  • Data Source:
  • HPRD (in vivo)

GHR

SOCS1

Gene Name growth hormone receptor suppressor of cytokine signaling 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Iron status biomarkers ( 19084217)
  • Response to taxane treatment (docetaxel) ( 23006423)
  • Systemic lupus erythematosus ( 18204098)
Protein-Protein Interactions 33 interactors: AP2A1 BTRC CISH DUSP7 GH1 GH2 GRB10 GRB2 IRS1 JAK1 JAK2 NCOA6 PIK3R1 PLCG1 PTPN1 PTPN11 PTPN13 PTPN2 PTPN3 PTPN6 PTPN9 PTPRB PTPRH SGTA SHC1 SOCS1 SOCS2 SOCS3 STAT3 STAT5A STAT5B STUB1 TYK2 40 interactors: ATM AXL COMMD1 CRK CSF1 CSF1R CXCR4 CYTIP EGFR ERBB2 FLT3 FYN GHR GRB2 IFNGR1 IGF1R IL2RB INSR IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 RELA TCEB1 TCEB2 TEC TEK TIRAP TRIM8 VAV1 VAV2
Entrez ID 2690 8651
HPRD ID 02971 04669
Ensembl ID ENSG00000112964 ENSG00000185338
Uniprot IDs P10912 O15524 Q4JHT5
PDB IDs 1A22 1AXI 1HWG 1HWH 1KF9 2AEW 3HHR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  stat5b  step  sustaining 
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
Tagcloud (Difference) ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  stat5b  step  sustaining 
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
Tagcloud (Intersection) ?